5种介入手术围术期抗菌药物预防使用干预前后对比分析  

Comparative Analysis of Perioperative Prophylactic Use of Antibiotics in 5 Interventional Operations before and after Intervention

作　　者：曲彩红[1] 朱洁明[2] 张永明[1] 戎利民[2] 单鸿[2] 

机构地区：[1]中山大学附属第三医院药学部,广州510630 [2]中山大学附属第三医院质管部,广州510630

出　　处：《中国药房》2014年第38期3572-3574,共3页China Pharmacy

摘　　要：目的:对比分析干预前后我院5种微创介入手术围术期抗菌药物的应用情况,以期为抗菌药物管理提供借鉴。方法:采取"干预—评价—反馈—再干预—再评价—再反馈"的模式,即首先在临床科室宣教抗菌药物相关文件精神,然后抽查病历,评价围术期抗菌药物使用情况,最后将有待改进意见反馈到临床科室。如此循环下去,同时密切关注该类手术切口感染及院内感染的发生情况。结果:经过近3年时间,我院介入手术围术期预防使用抗菌药物的比例从干预前的87.4%降到干预后的9.5%,抗菌药物的使用品种及疗程趋向合理,用药时机达标率为100%。干预前后均未发生切口感染。结论:除少部分具有发生感染的高危因素手术外,本研究中的5种介入手术绝大部分围术期没有必要预防性使用抗菌药物。OBJECTIVE： To analyze perioperative application of antibiotics in 5 microinvasive interventional operations before and after intervention comparatively, and to provide evidence for antibiotics management. METHODS： Adopting the model of ＂in- tervening-evaluating-feedback-reintervening-reevaluating-refeedback＂, in other words, disseminating related files of antibiotics to clinical department firstly, then evaluating the use of antibiotics during perioperative period by extracting medical records , finally providing related suggestions to clinical department, and so on; meanwhile, keeping an eye on the occurrence of nosocomial infec- tion and incision infection. RESULTS： After 3 years of intervention, the ratio of perioperative prophylactic use of antibiotics in in- terventional operations in our hospital decreased from 87.4% before intervention to 9.5% after intervention; the variety of antibiot- ics and treatment course tended to be reasonable, and the qualified rate of medication timing was 100%. No case of incision infec- tion occurred before and after intervention. CONCLUSIONS： Except for small part of operations with high risk of infection, it is not necessary to use antibiotics during perioperative period for 5 microinvasive interventional operations in this study.

关 键 词：经皮椎体成形术 放射性粒子植入术 射频消融术 经导管动脉化疗栓塞术 抗菌药物 合理用药 

分 类 号：R978.1[医药卫生—药品] R197.323[医药卫生—药学]