探讨踝肱指数对预测2型糖尿病慢性并发症的临床意义  

Clinical significance of ankle brachial index in the prediction of chronic complication of type 2 diabetes mellitus

作　　者：白杨 邓挺 

机构地区：[1]广州市东升医院,510000 [2]广州市广钢医院

出　　处：《中国实用医药》2014年第29期19-21,共3页China Practical Medicine

摘　　要：目的探讨踝肱指数(ABI)对预测2型糖尿病血管并发症的临床意义,并了解踝肱指数不同范围值对预测合并症的差异。方法分析298例2型糖尿病患者的踝肱指数测量值,并按常规标准分组,0.9<ABI<1.3为正常组、ABI≤0.9设为周围动脉病(PAD)组、ABI≥1.3设为动脉硬化组,并比较不同程度ABI分组间血管并发症发生率的差异。结果 PAD组的2型糖尿病患者与年龄、病程、收缩压、餐后2 h血糖、24 h尿微量白蛋白及血肌酐呈负相关,其心脑血管病变、肾脏疾病和糖尿病足发病率明显增高。而PAD组和动脉硬化组糖尿病足患病率显著高于正常组(P<0.05),呈类似"U"形分布的关系。结论踝肱指数与2型糖尿病血管合并症密切相关,ABI异常升高或降低可早期预测和预防糖尿病足的发生。Objective To explore the clinical significance of ankle brachial index （ABI） in the prediction of vascular complication of type 2 diabetes mellitus, and to gain cognition of the differences between different range values in prediction. Methods The ABI of 298 cases with type 2 diabetes mellitus were analyzed, and these cases were divided into three groups. The normal group had 0.9〈ABI〈1.3, the peripheral arterial disease （PAD） group had ABI ≤ 0.9, and the athelosclerosis group had ABI ≥ 1.3. Comparison was made between the different incidences of vascular complication with different ABI values. Results Patients with type 2 diabetes mellitus in PAD group had negative correlation with ages, symptoms, systolic pressure, postprandial 2 h blood glucose, 24 h microalbuminuria and serum creatinine. The incidences of cranial vascular disease, kidney disease, and diabetic foot were obviously increased. The incidences of diabetic foot in PAD group and atherosclerosis group were significantly higher than that of the normal group （P〈0.05）, and the distribution was U-form. Conclusion ABI is closely related to vascular complication of type 2 diabetes mellitus. The abnormal increase or decrease of ABI can predict and prevent diabetic foot early.

关 键 词：周围动脉病 踝肱指数 糖尿病足 2型糖尿病 

分 类 号：R587.2[医药卫生—内分泌]