Solitaire AB型支架机械取栓治疗颅内静脉窦血栓形成的疗效观察  

Curative effect observation of Solitaire AB stents in treatment of cranial venous sinus thrombosis

作　　者：谭衍 唐树洪 冼克聪[1] 边远[1] 李国平[1] 梁曦[1] 何雄英[1] 黄珊[1] 

机构地区：[1]广西省贵港市人民医院神经外科,537100

出　　处：《中华神经医学杂志》2014年第11期1131-1134,共4页Chinese Journal of Neuromedicine

基　　金：广西省贵港市科技攻关项目（1302020）

摘　　要：目的探讨Solitaire AB型支架机械取栓治疗颅内静脉窦血栓形成患者的临床疗效。方法广西省贵港市人民医院神经外科自2012年1月至2013年12月收治重症颅内静脉窦血栓形成患者40例．其中采用Solitaire AB型支架机械取栓治疗20例．单纯抗凝治疗20例，回顾性分析及比较2组患者的临床资料和疗效。结果出院30d后Solitaire AB型支架机械取栓治疗组患者GOS评分[（4．75±0．44）分]总体高于单纯抗凝治疗组[（3．75±1．29）分]，差异有统计学意义（P〈0．05）。Solitaire AB型支架机械取栓治疗组患者的治愈率、总有效率（80％、100％）均高于单纯抗凝治疗组（50％、80％），差异有统计学意义（P〈0．05）。单纯抗凝治疗组患者发生并发症8例（40．0％），SolitaireAB型支架机械取栓治疗组患者发生并发症2例（10．0％），差异有统计学意义（x^2=4．800，P=-0．028）。结论Solitaire AB型支架机械取栓可改善颅内静脉窦血栓形成患者的临床症状体征，提高临床疗效。Objective To investigate the clinical effect of Solitaire AB stents on cranial venous sinus thrombosis. Methods Forty patients with cranial venous sinus thrombosis, admitted to our hospital from January 2012 to December 2013, were chosen in our study; and they were divided into study group and control group （n=20） by different treatments. Patients from study group were treated with Solitaire AB stents, and those in control group were treated with conservative anticoagulation. Their clinical data were retrospectively analyzed and the clinical effect was compared in the two groups. Results The cure rate and total effective rate in the study group （80.0% and 100.0%） were higher than these in control group （50.0% and 80.0%）, with significant difference （P〈0.05）. Glasgow outcome scale （GOS） scores in the study group （4.75±0.44） were much higher than those in the control group （3.75± 1.29） 30 d after discharging from the hospital, with significant difference （P〈0.05）. Eight patients （40.0%） were noted having complications in the control group, while 2 （10.0%） were noted having complications in the study group, with significant difference （x^2=4.800, P=-0.028）. Conclusion it is good for patients with cranial venous sinus thrombosis to treat with SolitaireAB stents to improve clinical symptoms and clinical effect.

关 键 词：SOLITAIRE AB型支架 颅内静脉窦血栓形成 抗凝治疗 

分 类 号：R651.1[医药卫生—外科学]