血尿酸水平与老年人前列腺体积的相关性  

Relationship between Serum Uric Acid Level and Prostate Volume in Elderly Men

作　　者：李晨怡[1] 樊丹君[1] 孙百鸣[1] 

机构地区：[1]浙江医院干部保健科,杭州310012

出　　处：《医学研究杂志》2014年第10期156-158,共3页Journal of Medical Research

摘　　要：目的探讨血尿酸水平与老年人前列腺体积(PV)的相关性。方法纳入在笔者医院干部保健门诊体检的老年男性156例。收集病史,测量血压、身高、体重,计算体质指数(BMI),并检测血尿酸、甘油三酯、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、前列腺特异性抗原(PSA)。超声测量及计算前列腺体积(PV)。计算血尿酸四分位数,将研究对象分为4组,比较各组PV大小,并对PV与血尿酸水平进行相关性分析。结果 MS患者的血尿酸水平明显高于无MS者(402.5±76.9 vs 345.8±85.1μmol/L,P=0.000),PV亦明显大于后者(36.4±15.7 vs 26.2±13.0ml,P=0.000)。血尿酸四分位分组间PV大小分别为22.9±8.7、25.0±10.9、29.2±15.6、39.2±16.2ml,差异有统计学意义(P=0.000)。经线性相关分析,PV大小与血尿酸水平呈正相关。4组间MS的发生率分别为12.8%、17.9%、35.9%和46.2%,差异有统计学意义(P=0.003)。结论血尿酸水平与老年人PV显著相关。Objective To explore the relationship between serum uric acid level and prostate volume（PV） in elderly men.Methods Totally 156 elderly male cadres from the department of medical care for cadres in our hospital were enrolled in this study.Medical history was collected.Blood pressure,body weight,body height were measured and body mass index （BMI） was calculated.Serum uric acid,triglycerides （TG）,total cholesterol （TC）,low-density lipoprotein cholesterol（LDL-C）,high-density lipoprotein cholesterol （HDL -C）,fasting blood glucose（FBG） and prostate specific antigen （PSA） were assayed.PV was measured by abdominal ultrasound.We classified all participants on quartiles of serum uric acid levels,and PV were investigated.Then the relationship between PV and serum uric acid level was evaluated by correlation analysis.Results The mean concentration of serum uric acid was significantly higher in patients with MS than in participants without MS（402.5 ± 76.9 vs 345.8 ± 85.1 μmol/L,P =0.000）,and the mean value of PV was also significantly larger （36.4 ± 15.7 vs 26.2 ± 13.0ml,P =0.000）.The level of PV was 22.9 ±8.7,25.0 ± 10.9,29.2 ± 15.6 and 39.2 ± 16.2ml among participants in 4 groups respectively （P =0.000）.PV was positively correlated with serum uric acid level by linear correlation analysis.The prevalence of MS was 12.8%,17.9%,35.9%,46.2% respectively,and there was a statistically significant difference （P =0.003）.Conclusion Serum uric acid level is significantly associated with PV in elderly men.

关 键 词：前列腺增生 尿酸 代谢综合征 

分 类 号：R4[医药卫生—临床医学]