浅析埃博拉病毒致病机制  

Brief summary on pathogenic mechanism of Ebola virus

作　　者：盛子洋[1] 范东瀛[1] 安静[1] 

机构地区：[1]首都医科大学基础医学院微生物学教研室,北京100069

出　　处：《首都医科大学学报》2014年第5期529-532,共4页Journal of Capital Medical University

摘　　要：埃博拉病毒(Ebola virus,EBOV)属于丝状病毒科的单股负链RNA病毒,人体感染后可导致致命的埃博拉病毒病(Ebola viral disease,EVD)。当前EBOV广泛流行于非洲大陆,传染性强、致死率高、曾造成多次大暴发,严重威胁着疫区人们的健康和生命。然而目前EBOV的致病机制尚不明确,本文仅就EHF发病机制的最新进展做一综述,供广大同行参考。The Ebola virus（ EBOV）,a single strand negative RNA virus,belongs to Family Filoviridae. The infection can cause severe haemorrhagic fever（ EHF）. The virus distributes widely in Africa mainland and has caused continuous outbreaks because of its strong virulence and high infectivity. However,the pathogenesis of EHF remains unknown. This review will focus on recent progress of Ebola research to provide information for prevention and treatment of EBOV infection.

关 键 词：埃博拉病毒 出血热 致病机制 

分 类 号：R512.8[医药卫生—内科学]