后房型人工晶体植入的安全及稳定性  

Safety and stability of posterior chamber phakic intraocular lens implantation

作　　者：吕全[1] 袁均[2] 蔡奕琪[1] 刘轶[1] 

机构地区：[1]福建医科大学附属闽东医院眼科,福建省福安市355000 [2]湖北医药学院附属十堰市太和医院眼科,湖北省十堰市442000

出　　处：《中国组织工程研究》2014年第39期6386-6391,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:眼内屈光手术中有晶状体眼人工晶体植入已被用于屈光度过高及角膜厚度较薄的中高度屈光不正者,其具有可逆性和保留眼部调节力等优点。目的:通过与行准分子激光原位角膜磨镶手术矫正高度近视效果的对比,评价后房型有晶体眼人工晶体植入的安全性与稳定性。方法:纳入126例高度近视在校大学生,其中男女各63例,年龄(21.87±1.18)岁。将126例高度近视志愿者随机均分为试验组与对照组,试验组采用后房型有晶体眼人工晶体植入进行高度近视矫正,对照组采用准分子激光原位角膜磨镶手术进行高度近视矫正,随访1年观察两组裸眼视力、矫正视力、对比敏感度及不良反应,计算两组有效性指数与安全性指数。结果与结论:试验组有效性指数与安全性指数均优于对照组(P<0.05)。试验组随访1年明暗环境下的对比敏感度均高于术前,并且明暗环境下的对比敏感度均高于对照组。随访1年,对照组5例出现夜间视力下降及眩光,试验组1例出现夜间视力下降及眩光。表明后房型有晶体眼人工晶体植入在临床中是安全与稳定的,提高了视觉质量。BACKGROUND：Intraocular refractive operation with phakic intraocular lens implantation has been used in highly refractive errors patients with over-high diopter and thinner corneal thickness, which has the advantages of reversibility and retain the eye＇s accommodation. OBJECTIVE：To evaluate the safety and stability of posterior chamber phakic intraocular lens implantation in comparison with Lasik correction for high myopia. METHODS：Total y 126 col ege students with high myopia, 63 males and 63 females, aged （21.87±1.18） years, were randomly divided into test and control groups. In the test group, col ege students received posterior chamber phakic intraocular lens implantation, while those in the control group were subject to Lasik correction. During 1-year fol ow-up, naked vision, corrected visual acuity, contrast sensitivity, and postoperative untoward reaction were observed, and the effectiveness and safety indexes were calculated in the two groups. RESULTS AND CONCLUSION：The effectiveness and safety indexes in the test group were both superior to those in the control group （P〈0.05）. After 1 year of fol ow-up, the contrast sensitivity light and dark environment in the test group was significantly improved, which was also higher than that in the control group. Decreased night vision and glare was found in five cases of the control group and one case of the test group. These findings indicate that posterior chamber phakic intraocular lens implantation is safe and effective that can improve the visual quality in clinic.

关 键 词：生物材料 材料相容性 高度近视 屈光手术 后房型人工晶体 植入手术 对比敏感度 术后不良反应 视力稳定性 

分 类 号：R318[医药卫生—生物医学工程]