太原地区儿童中人偏肺病毒及人博卡病毒感染的初步研究  

Preliminary study on human metapneumovirus and human bocavirus infection among children in Taiyuan,from 2012 to 2013

作　　者：兰涛[1] 孙宇[2] 王乃昌[3] 高爱梅[1] 赵林清[2] 朱汝南[2] 钱渊[2] 贾云霞[1] 贾俊松[1] 刘燕[1] 

机构地区：[1]山西省人民医院儿科,太原030012 [2]首都儿科研究所病毒研究室 [3]山西省疾病预防控制中心病毒研究室

出　　处：《中华实验和临床病毒学杂志》2014年第5期377-379,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的 了解太原地区急性呼吸道感染（ARI）儿童中人偏肺病毒（hMPV）与人博卡病毒（HBoV）的流行病学及临床特征.方法 采集2012年11月至2013年2月因ARI至山西省人民医院儿科门诊就诊或住院的患儿咽拭子标本300例,应用实时PCR方法检测hMPV及HBoV.结果 所检测的300例标本中,hMPV检测阳性的标本为39例（13％,39/300）,HBoV检测阳性的标本为6例（2％,6/300）,主要导致急性下呼吸道感染（ALRTI）.hMPV感染在＜3岁的儿童中多见,其中1～2岁年龄组检出率较高.结论 在本研究的监测时间中,hMPV是太原地区ALRTI儿童的重要病原体之一,HBoV感染率相对较低.Objective To investigate the epidemic and clinical features on human metapneumovims （hMPV） and human bocavirus （HBOV） among pediatric patients with acute respiratory infection （ARI） in Taiyuan.Methods Clinical specimens of a total of 300 pediatric cases with acute respiratory infection were obtained during the period of Nov.2012 to Feb.2013.These patients were inpatients or outpatients who visited the department of pediatric in People＇ s Hospital Shanxi Province.Reverse transcription （RT） PCR methods were applied to detect hMPV and HBOV.Results Of the 300 clinical specimens,39 were hMPV positive （13%） and 6 were HBOV positive （2%）.HMPV and HBOV were main causes of acute lower respiratory infection （ALRTI）.The majority of children infected with HMPV were younger than 3 years old.High detection rates were found in children at the age of 1-2 years.Conclusion Our findings suggested that hMPV had been one of the important agents causing ALRTI in pediatric patients in Taiyuan.HBOV infection rates were relatively low.

关 键 词：偏肺病毒 人 博卡病毒 人 呼吸道感染 儿童 学龄前 

分 类 号：R725.1[医药卫生—儿科]