运动过度致脏器损伤机制及天然多糖干预作用的研究进展  

Progress in mechanisms of damage induced by hyperkinesis and intervention effect of natural polysaccharides

作　　者：谷枫[1] 王玉霞[2] 麻浩[2] 郭华[3] 单俊杰[2] 

机构地区：[1]中央民族大学体育学院,北京100081 [2]军事医学科学院毒物药物研究所,北京100850 [3]军事医学科学院门诊部,北京100850

出　　处：《中国药理学与毒理学杂志》2014年第5期788-793,共6页Chinese Journal of Pharmacology and Toxicology

基　　金：国家科技重大专项(2012ZX09301003-001)~~

摘　　要：运动适度有益身心健康,但长期运动过度则可会引起心、肝、肾、横纹肌以及免疫功能的损伤。近几年来,康复学家致力于寻找能预防和治疗运动损伤的天然药物。运动过度导致脏器损伤的可能机制包括免疫功能失调、激素紊乱、代谢异常和氧化损伤等。天然多糖可通过提高免疫功能、调节物质代谢和减轻自由基损伤等减轻运动过度性损伤。Physical training induces beneficial adaptations,but long excessive exercise may lead to severe damage to the skeletal muscles,liver,heart,kidneys and immune functions. Over the past few decades,health scholars have been searching for natural components that can prevent or improve the damage induced by hyperkinesis. The mechanisms of organ damage induced by long overtraining include immunosuppression,metabolism disorder,hormone disturbance,oxidative damage, etc. Natural poly-saccharides have interventional effects on these injuries,possibly by improving immunity,regulating metabolism and ameliorating free radical damage.

关 键 词：运动过度 损伤 多糖 

分 类 号：R874[医药卫生—运动医学]