巨大型尖锐湿疣17例临床分析  

Clinical Analysis of 17 Cases with Giant Condyloma Acuminatum

作　　者：尹光文[1] 李芳芳[1] 李旭阳[1] 黄云慧 宋飞娟 

机构地区：[1]郑州大学第一附属医院皮肤科,河南郑州450052

出　　处：《中国皮肤性病学杂志》2014年第11期1146-1148,共3页The Chinese Journal of Dermatovenereology

基　　金：河南省重点科技攻关项目(132102310517);河南省教育厅科学技术研究重点项目(13A320426)

摘　　要：目的分析巨大型尖锐湿疣的临床及病理特征,为临床医生诊治本病提供参考。方法对2002年4月-2012年12月资料完整的17例巨大型尖锐湿疣临床特征、组织病理、治疗及预后进行分析。结果 17例巨大型尖锐湿疣主要发生在外阴、肛周等部位,外观呈球形、条索形、分叶状等不同形态,表面呈菜花状、乳头状,体积均超过核桃大小。女性患者12例,男性5例。病理表现典型,可见角化过度、角化不全、乳头瘤样增生、棘层肥厚、挖空细胞等基本特点。采用综合治疗,随访期间未见癌变病例。结论巨大型尖锐湿疣临床相对少见,目前对巨大型尖锐湿疣在诊断标准、病理性质、规范化诊疗、临床预后等方法缺乏共识,提高临床医生对本病的本质认识有重要意义。Objective To analyze clinical and pathological characteristics of giant condyloma acuminatum, providing some references for dermatologists to diagnose and treat this disease. Methods A total of 17 patients,including 12 females and 5 males,with giant condyloma acuminatum were enrolled in this study from April 2002 to April 2012. Patients＇ clinical data, pathological features, treatment and prognosis were analyzed. Results The lesions mainly involved the labium and peri-anal. The lesions were spherical, cord, or lobulated walnutsize with caulifloweror papillary-like surface. The typical pathological manifestations included hyperkeratosis,parakeratosis, papillomatous hyperplasia, acanthosis, and koilocytes. Comprehensive treatment was employed No canceration occurred during the follow-up. Conclusion Giant condyloma acuminatum is relative rare in clinic. Due to the insufficient knowledge about diagnosis, pathological features, treatment and prognosis of this disease ,it is important to raise physician＇s awareness about the nature of this disease.

关 键 词：巨大型尖锐湿疣 临床特征 组织病理 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]