准分子光与窄谱紫外线治疗儿童局限性白癜风的临床疗效观察  

Clinical efficacy of 308 nm excimer light and 311 nm narrow-band ultraviolet in the treatment of localized vitiligo in children

作　　者：杜玮[1] 堵桂梅[2] 何春峰[2] 王杰[2] 杜华[2] 

机构地区：[1]深圳市儿童医院设备科,广东深圳518038 [2]兰州军区兰州总医院皮肤科

出　　处：《西北国防医学杂志》2014年第5期411-413,共3页Medical Journal of National Defending Forces in Northwest China

摘　　要：目的:评价308 nm准分子光与311 nm窄谱紫外线治疗儿童白癜风的疗效与安全性。方法:选择46例儿童局限性白癜风患者作为观察评价对象。治疗:采用自身对照,将皮损划分为308 nm准分子光区和311 nm窄谱紫外线照射区,每周治疗3次,共30次,记录治疗次数、累计照射剂量、疗效及不良反应。结果:15次光疗和30次光疗后,308 nm准分子光区皮损的有效率分别为51.16%,69.77%,311 nm窄谱紫外线治疗区的有效率分别32.56%、53.49%,差异均有统计学意义(P<0.05)。结论:两种方法治疗儿童局限性白癜风,308 nm准分子光疗效优于311nm窄谱紫外线。Objective： To evaluate the efficacy and safety of 308 nm excimer light and 311 nm narrow- band ultraviolet（311 nm NB-UVB） in treating localized vitiligo in children. Methods： A total of 46 children with localized vitiligo were included. The therapeutic effects were evaluated by self-comparison meth6d. The skin lesion were divided into two parts,one part was treated with 308 nm excimer light, the other ：part was treated with 311 nm NB-UVB, three times per week and altogether 30 times. The treatmenttimes, cumulative radiation dose, therapeutic efficacy and adverse reactions were all recorded carefully. Results：Afterl5 and 30 treatments,the effective rates were 51.16% and 6：9.77% in 308 nm excimer light group,and a2.56% and 53.49% in 311nm NB-UVB group respectively. The differences were statistically significant（P〈0.05）, Conclusion： 308 nm excimer light is more effective than 311nm narrow-,band ultravioletin treating children＇s localized vitiligo. ,

关 键 词：白癜风 儿童 308 nm准分子光 311nm窄谱紫外线 疗效观察 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]