静息心率与中老年人群颈动脉斑块检出率的关系  

The relationship between resting heart rates and detection rate of carotid artery plaques in the elderly

作　　者：黄宇玲[1,2] 王志军[2] 刘雪梅[3] 李雯[3] 王迈[3] 陈朔华 吴寿岭 

机构地区：[1]天津医科大学泰达国际心血管病医院,天津300450 [2]河北联合大学附属医院心内科 [3]河北联合大学附属开滦总医院超声科 [4]重症医学科 [5]心内科

出　　处：《中华高血压杂志》2014年第9期841-846,共6页Chinese Journal of Hypertension

基　　金：国家科技支撑计划项目(2008BAI52B03)

摘　　要：目的探讨静息心率与中老年人群颈动脉斑块检出率的关系。方法在参加2006-2007年健康体检的开滦（集团）有限责任公司在职及离退休职工101 510人中随机抽取5852人作为观察队列,于2010-2011年对观察队列进行健康体检,同时进行颈动脉超声检查,最终纳入5280人,按静息心率测量值分为〈60（n=690）,60-〈70（n=1979）,70-〈80（n=1750）,80-〈90（n=599）和≥90次/min组（n=262）,比较各组斑块检出率。采用Logistic回归分析颈动脉斑块的影响因素。结果 5280名中老年人群（男3172名,女2108名）,年龄（55.0±11.7）岁。静息心率〈60、60-〈70、70-〈80、80-〈90和≥90次/min组的颈动脉斑块检出率分别为47.4%、39.7%、40.4%、47.1%、55.7%;多因素分析结果表明,调整其他危险因素后,静息心率≥90次/min组发生颈动脉斑块的风险比60-〈70次/min组增加67%（OR1.67;95%CI1.20-2.31）。结论静息心率与颈动脉斑块检出率的关系呈J形曲线,静息心率≥90次/min是中老年人群发生颈动脉斑块的独立危险因素。Objective To explore the relationship between the resting heart rates （RHR） and detection rate of carot- id artery plaques in an elderly population. Methods In a cohort study during 2010 and 2011, a total of 5852 partic- ipants were randomly selected from 101 510 workers who were employed by or retired from Tangshan Kailuan Com- pany and finally 5280 cases were included. Carotid artery plaques were detected with ultrasound. The detection rate of carotid artery plaque was compared in the cohort according to the RHR： 〈60（n= 690）, 60-〈70 （n= 1979） , 70-〈80（n=1750） , 80-〈90（n=599） , and ≥90 beats/min（n=262）. Logistic regression analysis was adopted to analyze the influential factors associated with carotid artery plaque. Results There were 5280 elderly participants aged （55.0±11.7） years old, including 3172 males and 2108 females. The detection rate of carotid ar- tery plaque was 47.4%, 39.7%, 40.4%, 47.1% and 55.7% respectively in the subjects with RHR〈60, 60-〈70, 70-〈80, 80-〈90 and ≥90 beats/rain. Compared with the participants with the RHR 60-〈70 beats/ min, the risk of developing carotid plaque was increased by 67% in those with RHR≥90 beats/rain after adjusting for all influential factors （OR 1.67; 95% CI 1.20-2.31）. Conclusion The relationship between RHR and the detection rate of carotid plaque follows a J-shaped curve, and the RHR of more than 90 beats/rain is an independent risk factor of carotid artery plaque in the elderly.

关 键 词：静息心率 颈动脉斑块 中老年人群 危险因素 

分 类 号：R543.4[医药卫生—心血管疾病]