Topics of interest-‘Developing novel animal models for complex disorders' Edition 2  

作　　者：高伟坚 

出　　处：《中国实验动物学报》2014年第5期100-100,共1页Acta Laboratorium Animalis Scientia Sinica

摘　　要：本期高伟坚博士将向读者介绍"西登哈姆氏舞蹈病(小舞蹈病)"和"相关的神经精神障碍大鼠动物模型"。此文献向读者解读了:一篇高质量的文章,作者的原始构思和巧妙实验方法。有助于读者清楚地认识到由想法到实验设计的完成和论文撰写工作。While it can be challenging for any research team to develop a novel, reproducible animal model for their investigations into complex disorders or syndromes, it goes without mentioning that simple, clear and well designed experiments based on fundamental hypotheses remain key to achieving a high level of success. In this article, I bring your attention to some excellent research carried out by Brimberg et al （2012）, whose work helped produce a novel rat model for the study of neuropsychiatric disorders, specifically Sydenham＇ s chorea （SC） and Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections （PANDAS）.

关 键 词：小舞蹈病 大鼠动物模型 神经精神障碍 EDITION 2 实验设计 实验方法 challenging dopamine GLCNAC HEMOLYTIC 

分 类 号：TP751.1[自动化与计算机技术—检测技术与自动化装置]