老老年高血压患者不同舒张压水平低密度脂蛋白特征分析  

Analysis on low-density lipoprotein characteristic in very elderly hypertensive patients with different levels of diastolic blood pressure

作　　者：魏艺[1] 贾岱琳[1] 胡元会[1] 肖响[2] 孟昊[2] 宋庆桥[1] 杨传华[3] 

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学,北京100029 [3]山东中医药大学第一附属医院,山东济南250014

出　　处：《现代中西医结合杂志》2014年第33期3652-3654,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2012109)

摘　　要：目的 探讨老老年高血压患者不同舒张压水平低密度脂蛋白的特征。方法 选择老老年高血压患者259例，均询问病史、行常规生化检查和动态血压监测；按照24 h 平均舒张压水平分组：1组≥80 mmHg（1 mmHg ＝0．133 kPa），2组70～79 mmHg，3组60～69 mmHg，4组50～59 mmHg，5组＜50 mmHg；比较不同动态舒张压水平低密度脂蛋白水平。结果 低密度脂蛋白水平1组（3．27±0．69）mmol／L，2组（2．48±0．56）mmol／L，3组（2．70±0．57） mmol／L，4组（2．67±±0．63）mmol／L，5组（2．82±0．62）mmol／L，其中2组低密度脂蛋白水平最低，1，5组显著高于2，3，4组（P 均＜0．05），5组低密度脂蛋白水平由低到高依次为2组＜4组＜3组＜5组＜1组。结论 老老年高血压患者舒张压水平宜控制在70～79 mmHg，低密度脂蛋白水平最低，提示24 h 平均舒张压70～79 mmHg 或许可以成为老老年高血压患者舒张压的合理范围；舒张压过高和过低预后均较差。Objective It is to approach the low -density lipoprotein characteristic in very elderly hypertensive patients with different levels of diastolic blood pressure.Methods 259 hospitalized cases of very elderly hypertensive patients were selected and asked about the history, routine biochemical tests and ambulatory blood pressure monitoring; then divided them accordance with the 24 -hour average diastolic pressure level： group 1 with levels of ≥ 80 mmHg, group 2 set of 70 to 79 mmHg, group 3 set of 60 to 69 mmHg, group 4 set of 50 to 59 mmHg, group 5 set of 〈50 mmHg; the levels of LDL of different dynamic diastolic blood pressure were compared.Results The level of LDL was （3.27 ±0.69） mmol/L of group 1,（2.48 ±0.66） mmol/L of group 2, （2.70±0.77） mmol/L of group 3, （2.67 ±0.83） mmol/L of group 4 and （2.82±0.62） mmol/L of group 5 respectively; the level of LDL in group 2 was the minimum; the LDL levels of group 1 and 5 were higher than those of group 2, 3, 4 （all P 〈0.05）; the LDL level of five groups from low to high for the group 2 〈group 4 〈group 3 〈group 5 〈group 1.Conclusion The level of diastolic blood pressure in patients with hypertension should be controlled at 70 to 79 mmHg, the level of LDL is the lowest; this prompt that 24 -hour mean diastolic blood pressure of 70 to 79 mmHg could become very elderly hypertensive patients with diastolic reasonable range, and the diastolic blood pressure of too high and too low will be a poor prognosis.

关 键 词：老老年 高血压 舒张压 低密度脂蛋白 

分 类 号：R544.1[医药卫生—心血管疾病]