舒乐冲剂质量标准研究  

Study on Quality Standard for Shule Granules

作　　者：张淑香[1] 王萌影[2] 王术平[1] 

机构地区：[1]黑龙江中医药大学中医药研究院,哈尔滨150040 [2]黑龙江中医药大学附属第一医院

出　　处：《中国药师》2014年第10期1765-1767,共3页China Pharmacist

基　　金：黑龙江省科技攻关项目(编号:GC07C34506)

摘　　要：目的:建立舒乐冲剂的质量标准。方法:采用TLC对舒乐冲剂中当归、三七、路路通和益母草进行定性鉴别,采用HPLC法对舒乐冲剂中三七皂苷R1、人参皂苷Rg1含量进行测定。结果:定性鉴别斑点清晰,分离度好,专属性强;三七皂苷R1和人参皂苷Rg1两种主成分含量分别为0.1666,0.6818 mg·g-1。结论:建立的舒乐冲剂TLC和HPLC-UV含量测定方法简便、准确、重复性好,可作为舒乐冲剂质量控制的方法。Objective：To establish the quality standard for Shule granules. Methods：By TLC, Angelic asinensis, Panax pseudog-inseng, Fructus liquidam-baris and Leonurus in Shule granules were qualitatively identified;and contents of notoginsenoside R1 and gin-senosides Rg1 in Shule granules were quantitatively determined by HPLC. Results： In the qualitative identification, the clear spots showed good resolution and specificity. The content of notoginsenoside R1 and ginsenosides Rg1 , two main ingredients in Shule gran-ules, was 0. 166 6 and 0. 681 8 mg·g-1 , respectively. Conclusion：The TLC and HPLC-UV determination method is simple, accu-rate and reproducible, and can be used as the quality control method for Shule granules.

关 键 词：舒乐冲剂 薄层色谱鉴别 含量测定 

分 类 号：TQ460.72[医药卫生—药物分析学]