七叶灵颗粒质量标准研究  

Quality Standard for Qiyeling Granules

作　　者：顾嘉钦[1] 沈云婕[1] 朱珺[1] 

机构地区：[1]上海交通大学附属胸科医院药剂科,上海200030

出　　处：《中国药师》2014年第11期1830-1832,共3页China Pharmacist

基　　金：上海市科委基金项目(编号:12401902500);上海市胸科医院科技发展基金项目(编号:YZ11-21)

摘　　要：目的：建立七叶灵颗粒的质量标准。方法：采用薄层色谱法对黄芪、柚皮苷进行定性鉴别;采用高效液相色谱法对黄芪甲苷进行含量测定。结果：定性鉴别阴性无干扰,分离度高;黄芪甲苷线性范围为0.166-1.104μg（r=0.999 1）,平均回收率为97.27%,RSD为1.3%（n=6）。结论：所建标准可以用于七叶灵颗粒的质量控制。Objective：To establish the quality standard for Qiyeling granules. Methods：Astragali Radix and naringin were identified by TLC. The content of astragaloside A was determined by HPLC. Results：The qualitative identification was with high resolution and without interference from the negative substances. The linear range of astragaloside A was 0. 166-1. 104 μg（r=0. 999 1）, and the average recovery was 97. 27%（RSD=1. 3%,n=6）. Conclusion：The method can be used in the quality control of Qiyeling granules.

关 键 词：七叶灵颗粒 质量标准 薄层色谱法 高效液相色谱法 

分 类 号：TQ460.72[医药卫生—药物分析学]