糖基化三氮唑水杨酸白杨素酯的合成与结构表征  

Synthesis and structure characterization of chrysin glycosyltriazole salicylic acid esters

作　　者：景临林[1] 范小飞[1] 马慧萍[1] 樊鹏程[1] 贾正平[1] 

机构地区：[1]兰州军区兰州总医院药剂科,甘肃兰州730050

出　　处：《化学研究》2014年第6期597-600,共4页Chemical Research

基　　金：国家自然科学基金项目(81202458);全军医药科研"十二五"面上项目(CLZ12JA04);中国博士后科学基金(2012M521926)

摘　　要：根据药物拼合原理,以水杨酸为桥联基将糖基化三氮唑结构引入白杨素分子中,合成了4个糖基化三氮唑水杨酸白杨素酯衍生物,产物结构经核磁共振谱氢谱、红外光谱、质谱和元素分析确认.According to ＂combination principle＂, four chrysin glycosyltriazole salicylic acid esters derivatives were synthesized by introducing glycosyltriazole unit into the molecule of chrysin with salicylic acid as the linker. The structure of as-synthesized products was characterized by nuclear magnetic resonance spectroscopy, infrared spectrometry, electron ionization mass spectrometry and elemental analysis.

关 键 词：白杨素 糖基化三唑 水杨酸 合成 结构表征 

分 类 号：O629.9[理学—有机化学]