钯催化剂催化交叉偶联反应形成P-C键和复杂含磷化合物的研究进展  

Research progress of cross-coupling reaction catalyzed by palladium catalyst affording P-C bond and Pcontaining complicated compound

作　　者：任铁钢[1] 补朝阳[2] 黎桂辉[3] 李勇喆[1] 何志鹏[1] 

机构地区：[1]河南大学化学化工学院,河南开封475004 [2]新乡学院化学化工学院,河南新乡453000 [3]河南大学特种功能材料教育部重点实验室,河南开封475004

出　　处：《化学研究》2014年第6期641-647,共7页Chemical Research

基　　金：河南省科技厅科技攻关项目(142102210559);河南省教育厅自然科学基金(13B150921)

摘　　要：综述了利用金属钯催化交叉偶联反应形成P-C键以合成各种复杂的含磷化合物特别是手性膦配体的研究进展;介绍了参加偶联反应的不同价态的P化合物亲核试剂,以及卤代烯烃、卤代芳烃、三氟甲磺酸烯基脂、三氟甲磺酸芳基脂、乙烯基硼酸脂等亲电试剂;探讨了相应的偶联反应的反应条件、反应机理及其在材料、医药、农药等领域的应用.A review is provided of the research progress of palladium-catalyzed cross-coupling reaction affording new P--C bond and P-containing complicated compound like chiral phosphine ligand specially. The P-containing nucleophilic reagents with different valences of phosphorous as well as the electrophilic reagents including alkenyl halide, aryl halide, alkenyltriflate, tryltriflate, and vinylboronate are introduced. Moreover, the reaction conditions for relevant crosscoupling reactions and the coupling reaction mechanism as well as the application of the coupling reaction in the fields of material, medicine, and pesticide are discussed.

关 键 词：钯催化剂 交叉偶联反应 P-C键形成 磷化物 

分 类 号：O643.3[理学—物理化学]