孕妇细菌性阴道病与羊膜腔感染相关性分析  

Correlation between bacterial vaginosis in pregnant women and intra amniotic infections

作　　者：黄丽娜[1,2] 范琦慧[2] 江静逸[1] 吴瑞瑾[1] 

机构地区：[1]浙江大学医学院附属妇产科医院妇产科,浙江杭州310006 [2]宁波市妇女儿童医院妇产科,浙江宁波315000

出　　处：《中华医院感染学杂志》2014年第22期5654-5656,共3页Chinese Journal of Nosocomiology

基　　金：浙江省人口计生委基金资助项目(JSW2013-B011)

摘　　要：目的探讨孕晚期细菌性阴道病(BV)与羊膜腔感染的关系对BV正规治疗,以降低感染率。方法选取2012年8月-2013年8月在医院产检诊断为BV并在医院分娩的孕妇355例,将其分为A组115例未治疗的孕妇与B组正规治疗的孕妇240例,对其绒毛膜羊膜炎发生率及羊水培养病原菌检出率进行比较分析。结果 A组孕妇发生绒毛膜羊膜炎13例,发生率11.3%,羊水培养阳性率5.2%;B组孕妇发生绒毛膜羊膜炎8例,发生率3.3%,羊水培养阳性率1.7%;A组绒毛膜羊膜炎发生率及羊水培养阳性率明显高于B组;羊水培养共检出10株病原菌,大肠埃希菌4株、阴道加德纳菌3株、类杆菌、消化链球菌、动弯杆菌各1株。结论孕晚期细菌性阴道病增加羊膜腔感染的发生率,正规治疗细菌性阴道病能使羊膜腔感染发生率明显降低。OBJECTIVE To explore the relationship between the third trimester bacterial vaginosis （BV） and the in‐tra amniotic infections so as to conduct the regular treatment and reduce the incidence of infections .METHODS A total of 355 maternals who were diagnosed as the BV in the prenatal testing and gave birth in the hospital from Aug 2012 to Aug 2013 were enrolled in the study and divided into the group A with 11 cases （ without any treat‐ment） and the group B with 240 cases （ with standard treatment ）;the incidence of chorioamnionitis and the isola‐tion rates of pathogens from amniotic fluid culture were observed and compared between the two groups .RESULTS The chorioamnionitis occurred in 13 cases in the group A with the incidence rate of 11 .3% ,and the positive rate of culture of amniotic fluid was 5 .2% ;the chorioamnionitis occurred in 8 cases in the group B with the incidence of 3 .3% ,and the positive rate of culture of amniotic fluid was 1 .7% ;both the incidence rate of chorioamnionitis and the positive rate of culture of amniotic fluid of the group A were significantly higher than those of the group B . Totally 10 strains of pathogens have been cultured from the amniotic fluid ,including 4 strains of Escherichia coli , 3 strains of Gardnerella vaginalis ,1 strain of Bacteroides ,1 strain of Peptostreptococcus ,and 1 strain of Mobilun‐cus .CONCLUSION The third trimester bacterial vaginosis can increase the incidence of the intra amniotic infec‐tions ,and the regular treatment of the bacterial vaginosis can effectively reduce the incidence of the intra amniotic infections .

关 键 词：细菌性阴道病 羊膜腔感染 绒毛膜羊膜炎 胎膜早破 

分 类 号：R711.31[医药卫生—妇产科学]