自拟通腑理气方对小鼠肠道蠕动功能影响实验研究  

Experimental Study on Effects of Tongfu Liqi Decoction on Intestinal Peristalsis Function in Mice

作　　者：吴崑岚[1] 金黑鹰[1] 谈瑄忠[1] 姚航[1] 张金浩[1] 章蓓[1] 

机构地区：[1]南京中医药大学第三附属医院,江苏南京210001

出　　处：《辽宁中医药大学学报》2014年第11期35-37,共3页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:从体内、体外实验研究通腑理气方对小鼠肠道蠕动功能的影响。方法:通过实验对照研究,观察其对小鼠小肠运动、排便时间及数量等多方面药理作用。结果:结果显示该方在大剂量时可显著提高依文思蓝的小肠推进率;缩短复方地芬诺酯便秘小鼠的首便时间,显著增加DC便秘小鼠的便粒数。结论:通腑理气方能有效加强小鼠的小肠及结肠运动,加速排便作用。因此对于术后促进患者胃肠功能的恢复应有一定的作用。Objective：To investigate the effects of Tongfu Liqi Decoction on small intestine movement in vitro and in vivo.Methods：We observed pharmacological effects about the movement of small intestine,defecation time and quantity through comparative experimental studies.Results：The results showed that the small intestinal propulsion rate can be significantly improved at high doses.At the same time,the first defecation time can be shortened and defecation quantity can be increased for constipation model mice.Conclusions：It revealed that Tongfu Liqi Decoction can effectively strengthen the peristalsis of small intestine and colon,which also can accelerate defecation.Therefore,it may play a certain role in promoting the recovery of gastrointestinal function of postoperative patients.

关 键 词：通腑理气 肠蠕动 胃肠功能 

分 类 号：R256.3[医药卫生—中医内科学]