中西医结合干预冠心病稳定型心绞痛气虚血瘀证临床疗效观察  

Integrative Interventions Stable Angina Syndrome of Blood Stasis Due to Qi Deficiency Clinical Efficacy

作　　者：刘光颖[1] 张哲[1] 李峥[1] 杨关林[2] 

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032 [2]辽宁中医药大学,辽宁沈阳110847

出　　处：《中华中医药学刊》2014年第11期2616-2619,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家科技支撑计划项目(2009ZX09502-99)

摘　　要：目的:中西医结合干预冠心病稳定型心绞痛气虚血瘀证临床疗效观察。方法:应用健脾益气、活血化瘀法结合西医标准治疗干预冠心病稳定型心绞痛气虚血瘀证,将240合格受试者采取中央随机化方法分至试验组与对照组,结合盲法、安慰剂对照,疗程8周,随访18周,观察西雅图生存质量(SAQ)变化以及心电图变化来评价临床疗效。结果:治疗前各基线指标比较差异无统计学意义(P>0.05),具有可比性。治疗后,西雅图心绞痛量表各个维度评分试验组较对照组提高,差异具有统计学意义(P≤0.05)。心电图各导联下降值好转情况试验组好于对照组,差异具有统计学意义(P>0.05)。结论:中西医结合干预可以提高冠心病稳定型心绞痛气虚血瘀证患者生存质量,疗效确切。Objective ： To observe the clinical efficacy of integrative intervention stable angina syndrome of blood stasis due to qi deficiency. Methods ： Strengthening Spleen Qi and promoting blood circulation method combines Western standard was used for stable angina syndrome of blood stasis due to qi deficiency. 240 qualified participants were taken to a central randomization methods of test and control groups, combined blinded, placebocontrol for 8 weeks, followed up for 18 weeks, and the quality of life in Seattle （SAQ） changes and ECG changes were evaluated. Results：The difference between the pre - treatment baseline indicators had no significant （ P 〉 0.05 ）. After treatment, the Seattle Angina Scale score of each dimension was improved more in the experimental group than that in the control group and the difference was statistically significant （P〈0.05）. The value of each lead ECG situation improved more significantly in test group than that in control group and the difference was statistically significant （ P 〉 0. 05 ）. Conclusion ： Integrative interventions can improve the quality of stable angina syndrome of blood stasis due to qi deficiency with a significant effect.

关 键 词：冠心病 气虚血瘀证 疗效观察 

分 类 号：R541.4[医药卫生—心血管疾病]