中医辨证联合人工泪液治疗干眼症的疗效  

Clinical Effects of Combined Therapy of Artificial Tears and Syndrome Differentiation on Xerophthalmia

作　　者：何陈亮[1] 胡振仙[1] 李永波[1] 

机构地区：[1]浙江省立同德医院眼科,浙江杭州310012

出　　处：《中华中医药学刊》2014年第11期2753-2755,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科研计划项目(2010ZA012)

摘　　要：目的:考察中医辨证联合人工泪液治疗治疗干眼症的临床效果。方法:选取2009年1月-2010年1月我院眼科门诊的干眼症患者124例,随机分为对照组(人工泪液)和实验组(人工泪液+中医辨证),治疗1个月后,比较两组患者有效率、眼部症状、泪膜破裂时间(BUT)、泪液分泌量(SIT)、角膜荧光染色(FL)、角膜表面规则性指数(SRI)和角膜表面不对称指数(SAI)。结果:对照组总有效率57.3%,实验组总有效率79.3%,两组比较差异具有统计学意义(P<0.05);两组患者在异物感和视疲劳评分无统计学差异(P>0.05),实验组眼干涩和眼红评分显著优于对照组(-2.16±0.97vs-1.39±1.19,P<0.01;-0.97±0.60vs-0.20±0.41,P<0.01)。在FL和SIT指标中,实验组显著优于对照组(1.51±0.16vs2.02±0.18,P<0.05;4.51±0.53vs3.72±0.37,P<0.05),在BUT指标中,实验组优于对照组(5.51±0.75vs5.22±0.82,P<0.05);在SRI和SAI指标中,实验组均优于对照组(0.53±0.35vs0.66±0.41,P<0.05;0.42±0.25vs0.52±0.32,P<0.05)。结论:人工泪液联合中药可有效提高患者视功能,改善干眼病症状。Objective ： To investigate the effect of artificial tears and syndrome differentiation on xerophthalmia. Methods： We selected 124 cases of xerophthalmia patients from January 2009 to January 2009 in our hospital. Those people were divided into control group （artificial tears） and experimental group （artificial tears ＋ syndrome differentiation）. After treatment for one month, we compared two groups rate of treatment, rupture time （BUT）, tear secretion （SIT） and corneal fluorescence staining （FL） , corneal surface regularity index （SRI） and corneal surface asymmetry index （SAI）. Results ： The effective rate in control group was 57.3% and in the experimental group it was 79.3%. Between two groups there was significant difference （P 〈 0.05 ）. There was no statistical difference in foreign body sensation and visual fatigue scores between two groups （ P 〉 0.05 ）. As for dry eyes and envy score, experimental group was better than control group. Experimental dry eyes and envy score were significantly better than that of control group（ -2.16 ±0.97vs - 1. 39 ± 1.19, P 〈 0.01 ; - 0.97 ± 0.60vs - 0.20 ±0.41, P 〈 0.01 ）. As for SIT and FL, the experimental group was significantly better than the control group （ 1.51 ± 0.16 vs 2. 02 ± 0.18,P 〈 0.05 ; 4.51 ± 0.53 vs 3.72 ± 0.37, P 〈 0.05 ）. As for BUT, the experimental group was better than that of the control group （5.51 ± 0.75 vs 5.22 ±0.82, P 〈 0. 05 ）. As for SRI and SAI, the experimental group was better than the control group （0.53 ± 0.35 vs 0.66 ± 0.41, P 〈 0.05 ; 0. 42 ± 0.25 vs 0. 52 ± 0.32, P 〈 0.05 ）. Conclusion： Artificial tears combined with traditional Chinese medicine could effectively improve patients visual function and improve xerophthalmia symptoms.

关 键 词：人工泪液 中药 干眼症 

分 类 号：R816.97[医药卫生—放射医学]