新型中性载体水杨酸根离子选择性电极的研究  

Study on Selective Salicylate Electrode Based on a Novel Neutral Carrier

作　　者：陈晓玉[1] 但建明[1] 潘伯广 齐誉[1] 洪成林[1] 

机构地区：[1]石河子大学化学化工学院/新疆生产建设兵团化工绿色过程重点实验室/省部共建国家重点实验室培育基地,石河子832000

出　　处：《石河子大学学报（自然科学版）》2014年第4期500-503,共4页Journal of Shihezi University(Natural Science)

基　　金：石河子大学高层次人才科研启动项目(RCZX200930)

摘　　要：由于水杨酸在医药及化妆品等方面广泛应用,其使用过量又会造成极大危害,因此,设计一种性能优异的水杨酸根离子选择性电极具有重要的意义。本文研制了一种以水杨醛缩1,3-丙二胺合铜(Ⅱ)([Cu(Ⅱ)-Schiff])为中性载体的PVC膜阴离子选择性电极,采用电化学方法对其性能进行表征,选用紫外光谱研究了该电极对Sal-的响应机理,并将电极初步应用于实际样品分析。结果表明:此电极对Sal^-具有较好的电位响应,其在pH=5.0的磷酸盐缓冲体系中性能最佳,响应范围为1.0×10^(-1)~1.0×10^(-6)mol/L,检测下限为2.3×10^(-7)mol/L,斜率为-59.6 mV/dec,响应时间为t_(9596)为17 s,电极具有至少2个月的使用寿命,该电极用于阿司匹林及复方阿司匹林药片中水杨酸的测定是可行的。因此,本实验设计的离子选择性电极在测定药片里水杨酸含量方面具有一定的应用前景。The excess use of salicylic acid,used widely in medicine and cosmetics,could cause great harm,so designing a kind of excellent salicylic ion selective electrode would have the vital significance.This article selected N,N＇-bis （salicylidene）-l,3- propanediamine copper （II） Schiff base complex（[Cu（II）-Schiff]） as neutral carrier used in the study of PVC membrane anion selective electrode.Its performance was characterized by electrochemical methods and means,the electrode response mechanism was investigated by ultraviolet spectrum,and it was applied to detect actual samples preliminarily：The result showed that the electrode exhibits a near Nernstian response for Sal- over a wide concentration range（1.0×10-1-1.0×10-6 mol/L） with a slope -59.6 mV per decade and a detection limit of 2.3×10-7 mol/L in a pH range of 5.0.h has a fast response time of about 17 s. The electrode had been applied to the determination of aspirin and compound aspirin tablets with satisfactory results.Therefore, the ion-selective electrode designed has a certain application prospect in the aspect of salicylic acid content determination in the tablets.

关 键 词：席夫碱合铜配合物 中性载体 水杨酸根离子 离子选择性电极 

分 类 号：TQ150[化学工程—电化学工业]