认知行为干预对肺移植术后患者服药依从性的影响  

Effect of cognitive-behavioral therapy on medication compliance in patients after lung transplantation

作　　者：曹晓东[1] 黄云娟[1] 许正红[1] 朱亭立[1] 黄琴红[1] 朱雪芬[1] 闵群惠[1] 陈静瑜[1] 

机构地区：[1]无锡市人民医院心肺ICU,江苏无锡214023

出　　处：《护理学杂志》2014年第20期15-17,共3页

基　　金：无锡市医院管理中心医学技术重大项目(YGZF1109)

摘　　要：目的探讨认知行为干预对肺移植术后患者服药依从性、血药浓度和肺功能的影响。方法将52例肺移植术后患者随机分为观察组和对照组各26例,对照组给予常规治疗和护理,观察组在常规治疗护理的基础上实施认知行为干预,比较两组术后6个月和1年的服药依从性、血药浓度和肺功能指标的差异性。结果观察组术后6个月和1年的服药依从率分别为96.15%和92.31%,对照组为92.31%和69.23%;术后1年观察组服药依从性、血药浓度、第1秒用力吸气量显著高于对照组(P<0.05,P<0.01)。结论认知行为干预能提高肺移植患者的服药依从性,维持有效血药浓度,提高肺功能。Objective To explore the impact of cognitive-behavioral therapy on medication compliance, plasma concentration of anti-rejection drugs and lung function of patients after lung transplantation. Methods Fifty-two patients were divided into an observation group and a control group randomly, both of 26 cases. Then, the former received cognitive-behavioral therapy, while the latter received conventional treatment and care. Six months and 1 year after the operation, medication compliance,plasma concentration of drugs and lung function of two groups were compared. Results At 6 months and 1 year after operation, the medication compliance rates of the observation group were 96.15% and 92.31% respectively, while those of the control group were 92.31% and 69.23% respectively. Besides, the medication compliance,plasma concentration of anti-rejection drugs and maximal inspiratory capacity of the observation group were significantly higher than those of the control group after 1 year（P^0.05 ,P%O. 01）. Conclusion Cognitive-behavioral therapy can improve the compliance of lung transplant patients, maintain effective plasma concentration of anti-rejection drugs and improve lung function.

关 键 词：肺移植 认知行为干预 服药依从性 血药浓度 肺功能 

分 类 号：R473.6[医药卫生—护理学] R62[医药卫生—临床医学]