南川木波罗根皮的化学成分  

Chemical Constituents Occurring in Roots of Artocarpus nanchuanensis

作　　者：刘爱红[1] 胡志成[2] 任刚[2] 袁金斌[3] 易文芳[2] 彭加兵 元文君 

机构地区：[1]南昌大学分析测试中心,南昌330029 [2]江西中医药大学中药资源与民族药研究中心,南昌330004 [3]江西中医药大学现代中药制剂教育部重点实验室,南昌330004

出　　处：《中国实验方剂学杂志》2014年第22期91-94,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(81160509;81360475);江西省自然科学基金项目(2010GZY0163);江西省科技计划项目(20121BBG70019)

摘　　要：目的：研究南川木波罗根皮的化学成分。方法：采用硅胶、Diaion HP20大孔吸附树脂、MCI gel CHP 20P树脂凝胶、Sephadex LH-20凝胶、ODS等柱色谱分离手段,对南川木波罗根皮醇提物的乙酸乙酯部位进行化学成分的分离纯化,根据化合物的理化性质及光谱数据鉴定其结构。结果：分离了9个化合物,分别鉴定为4-羟基苯甲醛（p-hydroxybenzaldehyde）（1）,2,4-二羟基苯甲酸（2,4-dihydroxybenzoic acid）（2）,香豆酸（p-coumaric acid）（3）,儿茶素[（＋）catechin]（4）,（E）-阿魏酸甲酯[（E）-ferulic acid methyl ester]（5）,E-对-羟基肉桂酸甲酯（p-E-hedroxycinnamic acid methyl ester）（6）,norartocarpetin（7）,反式氧化白黎芦醇（trans-oxyresveratrol）（8）,moracin M（9）。结论：化合物1,2,5,6为首次从桑科植物中获得,化合物3为首次在波罗蜜属植物中发现,而化合物7~9为首次从南川木波罗中分离得到。Objective： To study the chemical constituents of roots of Artocarpus nanchuanensis. Method：The constituents were isolated from the ethyl acetate portion of 95% ethanol extraction of A. nanchuanensis roots by column chromatography over silica gel,Diaion HP20 macroreticular resin,MCI CHP 20 P gel,Sephadex LH-20 gel,ODS gel,etc. Their structures were elucidated by analysis of physical chemical properties and spectral data.Result： Nine compounds were isolated and their structures were identified as p-hydroxybenzaldehyde（ 1）,2,4-dihydroxybenzoic acid（ 2）,p-coumaric acid（ 3）,（ ＋） catechin（ 4）,（ E）-ferulic acid methyl ester（ 5）,p-E-hedroxycinnamic acid methyl ester（ 6）,norartocarpetin（ 7）,trans-oxyresveratrol（ 8）,moracin M（ 9）.Conclusion： Compounds 1,2,5 and 6 were isolated from Moraceae for the first time. Compound 3 was firstly reported the occurrence in the genus Artocarpus,and compounds 7-9 were characterized in A. nanchuanensis for the first time.

关 键 词：波罗蜜属 南川木波罗 乙酸乙酯部位 酚性成分 

分 类 号：R284.2[医药卫生—中药学] R284.7[医药卫生—中医学]