中药治疗子宫内膜异位症术后复发的系统评价  

Systematic Review of Chinese Herbal Medicine for Controlling Recurrence of Endometriosis after Operation

作　　者：崔阳阳[1,2] 孙伟伟[1] 赵瑞华[1] 

机构地区：[1]中国中医科学院广安门医院妇科,北京100053 [2]北京中医药大学,北京100029

出　　处：《山东中医药大学学报》2014年第6期529-533,共5页Journal of Shandong University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81173297)

摘　　要：目的 :系统评价中药抑制子宫内膜异位症术后复发的临床疗效和安全性。方法 :计算机检索Pub Med、EMBASE、CBM、EMCC、CNKI、VIP、SPRINGER、Wan fang(从建库至2013年1月),纳入以子宫内膜异位症保守或半保守术后患者为研究对象的随机或半随机对照的临床试验,对纳入研究的方法学质量使用Cochrane手册进行评价,用Revman 5.2进行统计分析。结果:10篇研究符合纳入标准,Meta-分析结果显示中药抑制内异症术后复发的总有效率、复发率与西药组无显著性差异(P=0.10、P=0.30),妊娠率高于西药组且有显著性差异(P=0.0003)。结论 :中药可有效抑制子宫内膜异位症术后复发,且不良反应少于西药,但由于纳入研究数量有限,可能存在局限性。Objective：To assess the efficacy and safety of Chinese Herbal Medicine for controlling the recurrence of endometriosis after operation （REO）. Methods：We searched PubMed,EMBASE,CBM,EMCC, CNKI,VIP, Springer,Wanfang （from the date of database establishment to Jan. 2013）. Randomized controlled trials （RCTs） and quasi-randomized controlled trials（quasi-RCTS） of patients with REO were collected. The quality of included studies were evaluated by JADAD and Cochrane handbook. Meta-analysis was performed by RevMan 5.2 software. Results：Total 10 RCTs or quasi-RCTs were included. Meta-analysis suggested that total effect rate and recurrence rate of REO treated with Chinese herbal medicine were similar to western medieine（P=0.10 and P=-0.30）. The pregnancy rate of REO treated with Chinese medicinal herbs was higher than that of western medicine（P=0.0003）. Conclusion：Chinese medicinal herbs,with fewer adverse effects may be effective for controlling REO. The evidence is not strong enough because of the small quatity of included studies.

关 键 词：中草药 子宫内膜异位症 术后复发 系统评价 随机对照试验 

分 类 号：R271.911.71[医药卫生—中西医结合]