积极性社区干预对慢性精神分裂症患者的疗效评估  

Effect evaluation of active community intervention to patients with chronic schizophrenia

作　　者：吴越[1] 张恒[1] 许凌峰[1] 张紫娟[1] 王妙妙[1] 陆鑫晓 

机构地区：[1]南京医科大学附属无锡精神卫生中心,江苏南京214151 [2]无锡市南长区社区卫生服务中心,江苏无锡214000

出　　处：《现代预防医学》2014年第22期4087-4090,4106,共5页Modern Preventive Medicine

摘　　要：目的评估积极性社区干预对慢性精神分裂症患者的疗效。方法 120例处于稳定期的社区慢性精神分裂症患者随机分为干预组和对照组各60例,在入组前、入组6个月和12个月后,分别采用阳性与阴性症状评定量表(PANSS)、Morningside康复状态量表(MRSS)评估患者临床症状和康复情况,并比较2组患者1年内的复发住院率。同时在相同时间点采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、家庭负担会谈量表(FIS)评定患者主要照料者的心理健康状况水平和家庭负担情况。结果干预组患者复发住院率1.67%,对照组患者为18.33%,2组差异有统计学意义(P均<0.01)。干预组患者第6个月、12个月时PANSS、MRSS评分低于对照组(P均<0.01),第12个月时干预组主要照料者SAS、SDS和FIS评分低于对照组(P均<0.01)。结论积极性社区干预能明显改善精神分裂症患者的临床症状和社会功能,降低复发住院率,同时有利于提高患者家属的心理健康水平和降低家庭照料负担。Objective This study aimed to evaluate the effect of active community intervention to patients with chronic schizophrenia. Methods 120 patients with stable chronic schizophrenia were randomly divided into an intervention group （n=60） and a control group （n=60）. All patients were followed up for one year and assessed with the Positive and Negative Syndrome Scale （PANSS）, the Morningside Rehabilitation Status Scale （MRSS） before intervention, and 6 and 12 months after intervention. The rate of re-hospitalization in one year were compared between the two groups. The patients＇ guardians were assessed with the Self-rating Anxiety Scale （SAS）, Self-rating Depression Scale （SDS）, the Family Interview Schedule （FIS） at the same time. Results The re-hospitalization rate of the intervention group was 1.67%, whereas that of the control group was 18.33% （P〈0.01）. The changes in the scales of PANSS, MRSS of the intervention group were significantly lower than those of the control group at the time of 6 months and 12 months after intervention （P〈0.01）. The changes in the scales of SAS, SDS and FIS of intervention group were significantly lower than those of the control group at the time of 12 months after the intervention （P〈0.01）. Conclusion Active community intervention can effectively alleviate the clinical symptoms and improve the social function of patients with schizophrenia. Meanwhile, it can reduce the rate of re-hospitalization of patients, reduce their family burden, and improve the psychological health of family members.

关 键 词：社区 慢性精神分裂症 积极性干预 

分 类 号：R193[医药卫生—卫生事业管理]