胆道感染患者胆汁细菌学及药敏分析  

Analysis on bile bacteria and drug sensititity in patients with biliary tract infection

作　　者：叶满[1] 

机构地区：[1]广西医科大学第七附属医院,广西梧州543001

出　　处：《现代预防医学》2014年第22期4133-4134,共2页Modern Preventive Medicine

摘　　要：目的了解胆汁培养主要病原菌的分布及抗生素耐药性,用以指导临床用药。方法取因各种胆道感染的301例病人胆汁进行细菌培养和药物敏感试验。结果 301份胆汁标本中123份检出细菌,阳性率40.86%。有12份复合菌生长,共检出细菌135株。革兰阴性杆菌89株(65.93%),革兰阳性球菌46株(34.07%)。检出率最高的菌是大肠埃希菌61例(45.19%),药物敏感性因菌种而异。结论胆道感染仍以革兰阴性杆菌为主,临床上不同病原菌对抗生素的耐药性不同,对胆道感染性疾病应进行胆汁培养及药物敏感试验,以指导临床合理用药。Objective The purpose of this study was to learn about the distribution of the bile bacteria and the resistance towards antibiotics, so as to guide the clinical prescription. Methods Investigation on the distribution of bile bacteria and the drug sensitivity was conducted by obtaining and analyzing the bile from 301 patients with biliary tract infection. Results One hundred and twenty-three bile samples contained bacteria out of the 301 samples. The positive rate was 40.86%. There were 12 samples containing multiple strains of bacteria, resulting in 135 identified bacteria. There were 89 gram-negative bacteria （65.93%）, and 46 gram-positive bacteria （34.07%）. Escherichia coli accounted for 61 samples （45.19%）, which was responsible for the highest detection rate. The drug sensitivity was different among different bacteria. Conclusion The biliary infection was mainly caused by gram-negative bacteria. The drug sensitivity of different bacteria was different. It is important to perform cultivation and drug sensitivity experiment on bile bacteria and it is of great value in clinical application for the doctors.

关 键 词：胆汁 细菌培养 药敏试验 

分 类 号：R378[医药卫生—病原生物学]