参芪降糖颗粒对2型糖尿病患者临床有效性的系统评价  

Treating Type 2 Diabetes Mellitus by Shenqi Jiangtang Granule Therapy: A Meta-analysis of Reduce Blood Glucose Efficacy Comparion

作　　者：方朝晖[1,2] 赵进东[1,2] 舒仪琼[1,2] 鲍陶陶[1,2] 王欢[1,2] 凌含鹏 谢峰涛 侍磊[3] 

机构地区：[1]安徽中医药大学第一附属医院,安徽合肥230031 [2]安徽省中医药科学院,安徽合肥230031 [3]安徽中医药大学,安徽合肥230031

出　　处：《江西中医药大学学报》2014年第5期32-34,38,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：国家中医药管理局中医药重点学科资助项目(20091221);国家重大科技专项(2010ZX09102);国家科技支撑计划项目(2012BA126B00);国家中医临床研究基地业务建设科研专项(JDZX201201);国家中医药管理局国家基本公共卫生服务项目(20131012)

摘　　要：目的:评价参芪降糖颗粒对2型糖尿病患者作用的有效性。方法:计算机检索Cochrane图书馆临床对照试验资料库、Pubmed Embase、中国生物医学文献数据库、中国期刊全文数据库、万方期刊数据库等相关资料,按照Cochrane系统评价的方法,客观评价纳入研究的质量,提取有效数据,采用RevMan 5.2软件进行Meta分析。结果:共纳入7个随机对照试验,包括617例患者。结果显示,参芪降糖颗粒能降低2型糖尿病患者空腹血糖[MD=1.06,95%CI(0.79,1.33),P<0.01],降低餐后2h血糖[MD=1.17,95%CI(0.81,1.52),P<0.01],提高临床疗效[RD=-0.18,95%CI(-0.26,-0.11),P<0.01]。结论:参芪降糖颗粒对2型糖尿病患者降糖作用是有效的。Objective ： To evaluate the reduce blood glucose efficacy of Shenqi Jiangtang Granule therapy type 2 diabetes mellitus. Meth- ods： Randomized controlled trials were electronically retrieved from Cochrane Library, Pubmed Embase, CBM, CNKI, Wanfang Data- base, and so on. All articles were assessed according to the Cochrane Handbook for Systematic Reviews of interventions and then effec- tive data were analyzed by RevMan 5.2 soft ware. Results：Seven randomized controlled trials involving 617 patients were included. Results of Meta- analysis showed that there was statistical difference in the Fasting plasma glucose[ MD = 1.06,95% CI （0.79,1. 33 ）, P 〈 0.01 ], 2h Postprandial blood glucose [ MD = 1.17,95 % CI （0.81,1.52 ）, P 〈 0.01 ], improve the clinical curative effect [ RD = - 0.18,95% CI （ - 0.26, - 0.11 ） ,P 〈 0.01 ]. Conclusion The treatment plan of Shenqi Jiangtang Granule therapy type 2 diabetes mellitus is efficacy.

关 键 词：参芪降糖颗粒 2型糖尿病 有效性 系统评价 

分 类 号：R289.5[医药卫生—方剂学]