绝经女性颈动脉粥样硬化的临床调研与病机探讨  

Pathogenesis and Syndrome Distribution of Carotid Artery Atherosclerosis in Menopausal Women

作　　者：陈燕 温雅[2] 丁元庆[3] 

机构地区：[1]河南省南阳市中医院老年病科,南阳473000 [2]山东中医药大学基础医学院,济南250355 [3]山东中医药大学附属医院高血压血脉理论及应用重点研究室,济南250011

出　　处：《中国中医药现代远程教育》2014年第21期9-11,共3页Chinese Medicine Modern Distance Education of China

基　　金：国家中医药管理局中医临床研究基地业务建设科研专项课题[No:JDZX2012111]

摘　　要：目的探讨绝经女性颈动脉粥样硬化(CAS)的病机与证候分布规律。方法采集临床绝经女性CAS患者的相关信息,运用统计学方法对患者的症状、病史及相关资料进行分析,筛选绝经女性CAS的危险因素。结果增龄,雌激素缺乏,鼾眠,嗜辛辣、甜食、咸味,被动吸烟,超重,腹型肥胖,高血压、高脂血症病史是绝经女性CAS的主要危险因素;绝经女性组与正常生育期女性组在雌激素水平、打鼾程度、肥胖、高血压、高血脂、CAS程度方面具有显著差异;证候分布在绝经早期以火热证居多,随着绝经年限的延长,雌激素水平降低,肝肾阴虚的程度愈甚。结论绝经女性CAS危险因素多端,其证候分布以火热证、肝肾阴虚证居多;阴虚火盛是绝经女性CAS发病的病理基础,阴虚失养、火盛灼脉是核心病机。Objective This paper is de signed to explore the pathogenesis and the distribution rule of syndrome of CAS in menopausal women. Methods After clinically acquiring the information of the menopausal women patients with CAS, we analyze the patient＇s symptoms, medical history and related data by statistical methods, filter the risk factors of CAS. Results The risk factors of CAS, such as age, deficiency of estrogen, snoring sleep, spice, sweety, salty, passive smoking, obesity, history of hypertension, history of hyperlipidemia are main in menopausal women. There is a remarkable difference in terms of the level of estrogen, snoring sleep, obesity, hypertension,hyperlipidemia and CAS between menopausal women and fertility period women. In the early stage of menopause, heat syndrome is dominant. With the prolonging of menopause year, the level of estrogen reduces, and yin deficiency of liver and kidney is more significant.Conclusions The risk factors of CAS in menopausal women are varied. In terms of the distribution of syndrome, heat syndrome and yin deficiency of liver and kidney are the main syndrome. Yin deficiency and heat excess are the basic pathology of CAS in menopausal women, the core pathogenesis is yin deficiency and heat excess burning the artery.

关 键 词：绝经女性 颈动脉粥样硬化 肝肾阴虚 火热 临床调研 病机 

分 类 号：R543.4[医药卫生—心血管疾病]