应用超声心动图探讨心脏再同步化治疗患者的应变率与左心室舒张功能的关系  

Evaluation on Left Ventricular Diastolic Function by Echocardiographic Strain Rate in Patients With Cardiac Resynchronization Therapy

作　　者：兰亭玉[1] 王浩[1] 孙欣[1] 

机构地区：[1]北京协和医学院中国医学科学院阜外心血管病医院超声科,北京市100037

出　　处：《中国循环杂志》2014年第11期899-902,共4页Chinese Circulation Journal

摘　　要：目的:本研究旨在应用二维斑点追踪超声心动图(2D-STE)技术探讨心脏再同步化治疗(CRT)患者2D-STE舒张早期应变率参数与左心室舒张功能之间的关系。方法:研究选取70例实施CRT的心力衰竭患者。应用2D-STE技术获取患者舒张期早期应变率,观察左心室舒张功能参数于CRT超声心动图不同反应组中变化差异。计算受试者工作特征曲线(即ROC曲线)下面积。结果:41例患者在12个月的随访中达到了CRT超声心动图反应标准的为CRT超声心动图反应组;29例为超声心动图未反应者为CRT超声心动图未反应组。41患者在CRT超声心动图反应组中观察到大多数评估左心室舒张功能的参数较基线显著改善。以2D-STE所测舒张早期应变率预测CRT超声心动图反应与否绘制ROC曲线。舒张早期纵向应变率预测CRT超声心动图反应性的ROC曲线下面积最大。结论:舒张早期纵向应变率预测CRT超声心动图反应性价值更大,可作为评价舒张功能的更为敏感指标。Objective： To explore the relationship between strain rate parameter and left ventricular diastolic function （LVDF） in patients with cardiac resynchronization therapy （CRT） by two-dimensional speckle tracking echocardiography （2D-STE）. Methods： A total of 70 heart failure （HF） patients with CRT were studied. The early left ventrieular diastolic strain rate was obtained by 2D-STE technology, the differences of left ventricular diastolic functional parameters to various CRT echocardiographic responses were observed. The area of relevant parameters under ROC curve was calculated by early left ventricular diastolic strain rate for predicting CRT echocardiographic response. Results： There were 41 patients presented as CRT echocardiographic responders at 12 months of follow-up period, 29 patients were non-responders. The most parameters of LVDF were significantly improved than the base line in 41 responders. The maximum area of 2D-STE derived parameters under ROC curve was obtained by LSRE predicted CRT echocardiographic response Conclusion： LSRE had greater value for predicting CRT echocardiographic response, it might be used as a sensitive index for evaluating LVDF in HF patients.

关 键 词：二维斑点追踪超声心动图 应变率 心脏再同步化治疗 左心室舒张功能 

分 类 号：R54[医药卫生—心血管疾病]