黄芩苷生物合成途径与生物技术研究进展  

Study Advance on Biosynthesis Pathway and Biotechnology of Baicalin

作　　者：雷桅[1] 税晓容[2] 胡侃[3] 

机构地区：[1]广东医学院心血管疾病研究室,广东湛江524001 [2]广东医学院血管外科研究室,广东湛江524001 [3]广东省农业厅种子管理总站,广东广州510500

出　　处：《北方园艺》2014年第22期185-189,共5页Northern Horticulture

基　　金：国家自然科学基金资助项目(81300035;81403044);广东省自然科学基金资助项目(S2013040012115)

摘　　要：黄芩苷是我国传统中药黄芩的主要黄酮类活性成分,具有很高的药用价值。近年来,随着植物次生代谢工程的发展,黄芩苷生物技术的研究也取得了重要成果。文章介绍了黄芩苷生物合成途径的关键酶,以及利用基因工程和生化技术进行代谢调控和遗传改良方面的最新进展,以期为黄芩苷优质药源的种质创新和分子育种提供参考。Baicalin is the main active ingredient belonging to flavonoids from the traditional Chinese medicine Scutellaria sp.,which possesses high medicinal value.In recent years,with the development of plant secondary metabolic engineering,there were some important advances about the studies on the baicalin biotechnology.In this paper,the key enzymes involved in the biosynthesis pathway of baicalin,the last progress of metabolic regulation and genetic modification based on gene engineering and biochemical techniques were reviewed,aiming to provide theoretical references for germplasm innovation and molecular breeding of high-quality resource of baicalin.

关 键 词：黄芩 黄芩苷 生物合成 生物技术 关键酶 

分 类 号：S567[农业科学—中草药栽培] Q946[农业科学—作物学]