我院子宫手术围手术期规范应用抗菌药物效果的研究  

The effect of perioperative use of antimicrobial agents in uterine surgery in our hospital

作　　者：崔艳[1] 于亚滨[1] 

机构地区：[1]首都医科大学附属北京妇产医院疾病预防控制及医院感染管理科,100026

出　　处：《北京医学》2014年第11期927-929,共3页Beijing Medical Journal

基　　金：首都医科大学附属北京妇产医院院内课题基金(201218)

摘　　要：目的：分析抗菌药物专项整治活动对我院子宫手术围手术期抗菌药物应用的影响。方法2011年1月1日至6月30日前为抗菌药物整治活动前，7月1日至12月31日为整治活动后。回顾性分析2011年在卫生部抗菌药物专项整治活动前后我院开腹子宫全切手术病例围手术期抗菌药物应用情况的差异。结果整治活动前后均无感染病例发生；达标的指标为住院患者抗菌药物使用强度（整治前为58.03 DDD，整治后为28.81 DDD），未达标但有好转的指标为子宫手术住院患者预防使用抗菌药物术前0.5~2 h内给药百分率（59.7%vs.22.2%，掊2=23.987，P﹤0.05）和Ⅱ类切口手术患者预防使用抗菌药物时间≤48 h（77.6%vs.1.0%，Fisher=107.9，P﹤0.05），无变化的指标为住院患者抗菌药物使用率，均为100%。这一指标尚未细化到按照病种进行评价的程度，有待医务工作者和医政管理者在今后的工作实践中继续研究摸索。结论规范应用抗菌药物在我院取得了一定的效果，有些指标尚未达到要求的控制水平，持续进行此项工作任重道远，抗菌药物使用率应制定针对病种的细化指标。Objective To study the effect of perioperative antimicrobial agents usage for uterine operation before and after antimicrobial remediation. Methods From January 1st to June 30th were the days before antimicrobial remedia-tion period, while from July 1st to December 31th were after remediation period. The difference between antimicrobial us-age before and after remediation was retrospectively compared. Open hysterectomy patients in our hospital in 2011 were included. Results No case of infection were identified before and after remediation. The intensity of antimicrobial us-age met the criteria for standardized perioperative antimicrobial usage by the Ministry of Health （28.81 DDD vs. 58.03 DDD）. The percentage of preventive antimicrobial usage 0.5~2 h before the operation （59.7%vs. 22.2%, P〈0.05）, and the duration of antimicrobial usage for Class II operation incisions （77.6%vs. 1.0%, Fisher=107.9, P〈0.05） were partially met the requirement of the Ministry of Health, although much improved after the remediation. There was no change in antimi-crobial usage before and after remediation, ie, 100%. Conclusion ＂Standardizing antimicrobial usage regulation＂ has achieved good results in our hospital. However, the standards are not met in some aspects. The percentage of antibiotic us-age should be tailored based on the subtypes of operation.

关 键 词：子宫手术 围手术期抗菌药物 

分 类 号：R96[医药卫生—药理学]