代温灸膏的抗炎作用研究  

Study on anti-inflammatory effect of Dai Wenjiu ointment

作　　者：彭攸灵[1] 李勇敏[2] 彭淑珍[2] 

机构地区：[1]湖南中医药高等专科学校,湖南株洲412012 [2]湖南省中医药研究院,湖南长沙410006

出　　处：《湖南中医杂志》2014年第10期148-149,共2页Hunan Journal of Traditional Chinese Medicine

摘　　要：目的:探讨代温灸膏的抗炎作用。方法:制备角叉菜致足跖肿胀大鼠、醋酸炎症小鼠及羧甲基纤维素钠炎症大鼠模型,观察代温灸膏对模型大鼠的抗炎作用。结果:代温灸膏可抑制由角叉菜引起的大鼠足跖肿胀,能抑制炎症引起的毛细血管通透性增加,对羧甲基纤维素钠引起大鼠腹腔白细胞游走有明显的抑制作用。结论:代温灸膏具有较好的抗炎作用。Objective： To investigate the anti - inflammatory effect of Dai Wenjiu ointment. Methods： A rat model of carrageen - induced footpad swelling, a mouse model of acetic acid - induced inflammation, and a rat mod- el of sodium carboxymethylcellulose - induced inflammation were established. The model animals were treated with Dai Wenjiu ointment. The anti - inflammatory effect of Dai Wenjiu ointment was assessed. Results ： For these model animals, Dai Wenjiu ointment inhibited carrageen -induced footpad swelling, capillary permeability increase due to inflammation,and abdominal leukocyte migration caused by sodium carboxymethylcellulose. Conclusion： Dai Wenjiu ointment has a good anti -inflammatory effect.

关 键 词：代温灸膏 抗炎作用 大鼠模型 实验研究 

分 类 号：R285.5[医药卫生—中药学]