Cu（II）间接光度法测定头孢氨苄胶囊含量  

Indirect Photometric Determination with Cu（II） in detection content of Cefalexin Capsule

作　　者：吴静 

机构地区：[1]河南省荣军医院,河南新乡453000

出　　处：《世界最新医学信息文摘》2014年第29期5-6,共2页World Latest Medicine Information Electronic Version

摘　　要：利用头孢氨苄降解产物中巯基（-SH）具有还原性，建立一种间接测定头孢氨苄的新方法。根据吸光度间接计算头孢氨苄的含量。溶液中参加反应Cu（II）的量C（μg·ml^-1）和头孢氨苄含量之间存在良好的线性关系，线性范围为0．8～20μg·ml^-1，检出限为0．4μg·ml^-1。To obtain a new method to determine cefalexin by indirect photometry, based on reducibility of-SH which is the degradation product of cefalexin. Then the content of cefalexin was indirect calculated by absorbance. There was a good linear relationship between Cu（II） and cefalexin which reacted in solution. The linear range was 0.8-20μg·ml^-1 and the limit of detection was 0.4 μg·ml^-1.

关 键 词：CU(II) 头孢氨苄 间接光度法 降解 

分 类 号：R917[医药卫生—药物分析学]