降钙素原在细菌性血流感染患者中的临床意义  

The clinical significance of procalcitonin in patients with bacterial bloodstream infection

作　　者：冷凌涵[1] 王平[1] 张丽涓[1] 

机构地区：[1]成都市第五人民医院重症医学科,四川成都611130

出　　处：《世界最新医学信息文摘》2014年第29期91-91,94,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨患者血清降钙素原（PCT）水平对区别血培养生长革兰阳性菌及阴性菌的临床意义。方法对ICU患者血培养阳性者分为革兰阴性菌组及革兰阳性菌组，每组患者各25例，对两组患者血清降钙素原进行定量测定，并对定量测定结果进行统计学比较。结果血培养生长革兰阴性菌患者PCT定量为（60．556±38．816）ng／ml，显著高于革兰阳性菌组PCT（15．397±15．657）ng／ml，差异有统计学意义（P〈0．05）。结论革兰阴性菌血流感染患者的降钙素原水平明显高于革兰阳性菌血流感染患者，PCT测定有利于早期判断细菌感染的类别，指导早期抗菌药物选择。Objective To investigate the clinical significance of serum procalcitonin （PCT） levels in distinguishing growth of Gram-positive and gram negative bacteria in blood culture.Methods ICU patients with positive blood culture were divided into Gram-negative bacteria group and Gram-positive bacteria group, with 25 cases in each group. The serum procalcitonin in two groups were detected by quantitative determination, results of which were compared in statistics. Results The PCT level in blood culture results of growth of Gram-negative bacteria patients was （60.556 ± 38.816） ng/ ml, which was significantly higher than （15.397 ± 15.657） ng / ml in Gram-positive bacteria group. The difference was statistically significant （P 〈0.05 ）. Conclusion The procalcitonin level in patients with bloodstream Gram-negative bacteria infections was significantly higher than that in patients with bloodstream Gram-positive bacteria infections. Determination of PCT was in favor of judging early bacterial infection category and guiding the early antibacterial agent selection.

关 键 词：降钙素原 血流感染 革兰阳性菌 革兰阴性菌 

分 类 号：R446[医药卫生—诊断学]