川栀子中京尼平苷的提取吸附工艺研究  

Research on Extraction and Adsorption of Geniposide from Sichuan Gardenia

作　　者：刘育容 丁克毅[1] 刘军[1] 

机构地区：[1]西南民族大学化学与环境保护工程学院.成都610041

出　　处：《天然产物研究与开发》2014年第11期1864-1867,1806,共5页Natural Product Research and Development

基　　金：国家自然科学基金项目(21176202);四川省应用基础研究项目(2012JY0098);西南民族大学研究生创新科研重点项目(CX2014SZ63)

摘　　要：研究了川栀子中有效成分京尼平苷的吸附提取工艺。通过正交实验设计,综合考察了提取时间、提取溶媒和料液比(栀子质量(g)与溶剂体积(m L)之比)等因素的影响,优化得到京尼平苷的最佳提取工艺为:水提2次,料液比1∶6,提取时间为1 h。选用HP-20、HPD-100、HPD-450、D-101、D-101A五种不去同型号的大孔吸附树脂,测定其对京尼平苷吸附性能,最终选定HPD–100型号的大孔吸附树脂作为最佳吸附材料。The process of extraction and adsorption geniposide from Gardenia collected in Sichuan province were studied by using of macroporous resin. Three factors such as the extraction time,extractlon solvent and solid-solvent ratio,were taken into consideration during orthogonal experimental design. The results shoved that the optimum extraction process was below：extracting twice with water,the ratio of solid to solvent equals 1：6 and the extracting time was 1 h. Five types of macroperous resin,i, e. ,HP-20,HPD-100,HPD-450,D-101 and D-101A were selected for the determination of their adsorption properties of genlpeside. Ultimately, HPD-100 was defined as the optimum adsorption material.

关 键 词：大孔树脂 栀子 京尼平苷 吸附 

分 类 号：R284.2[医药卫生—中药学]