水黄皮的化学成分和药理作用研究进展  

Research progress on chemical constituents of Pongamia pinnata and their pharmacological activities

作　　者：马建[1] 吴学芹[1] 陈颖[1] 栾晓莹 张娜[1] 李宁[2] 张鹏[1] 

机构地区：[1]天津中医药大学天津市现代中药重点实验室天津市中药化学与分析重点实验室,天津300193 [2]沈阳药科大学中药学院,辽宁沈阳110016

出　　处：《现代药物与临床》2014年第10期1183-1189,共7页Drugs & Clinic

基　　金：国家自然科学基金资助项目(81303183)

摘　　要：水黄皮Pongamia pinnata为豆科水黄皮属植物,广泛分布于东南亚国家的河堤与沿海地区。从中分离得到化学成分主要有黄酮类、三萜类、生物碱类、氨基酸等成分。现代药理学研究表明水黄皮具有抗菌、抗炎镇痛、抗溃疡和抗痢疾等作用。综述了近10年来水黄皮的化学成分和药理作用研究进展,为其药效物质基础、作用机制研究及开发利用提供理论依据。Pongamia pinnata, the plant of Pongamia Vent. In Leguminosae, is distributed mostly along the coasts and riverbanks in Southeast Asia area. The main chemical constituents isolated from P. pinnata are flavonoids, terpenes, alkaloids, amino acid and so on. Modern pharmacological studies have demonstrated that P. pinnata plays a role in antibacterial, anti-inflammatory, analgesic, anti-ulcer and anti-dysentery activities, etc. The past decade research progress on the chemical constituents of P. pinnata and their pharmacological activities are reviewed in this paper, which could provide a theoretical basis for the material basis of efficacy, mechanism of action and exploitation.

关 键 词：水黄皮 化学成分 黄酮类 药理作用 

分 类 号：R282.71[医药卫生—中药学]