Preparation and chromatographic characteristics of a novel 2,6-dimethyl-β-CD bonded HPLC chiral stationary phase  

作　　者：Qiu-Jin Peng Jun-Jiao Yang 

机构地区：[1]Beijing Key Laboratory of Environmentally Harmful Chemical Analysis, Beijing University of Chemical Technology

出　　处：《Chinese Chemical Letters》2014年第11期1416-1418,共3页中国化学快报（英文版）

摘　　要：A novel 2,6-dimethyl-b-CD bonded and silica based HPLC chiral stationary phase（CSP） was prepared.The diphenylmethane diisocyanate（MDI） was applied for the first time in the immobilization of 2,6-dimethyl-b-CD onto the surface of aminized silica gel under mild conditions. The composite materials obtained were used as the CSP for chiral separation processes and this kind of CSP exhibits good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.A novel 2,6-dimethyl-b-CD bonded and silica based HPLC chiral stationary phase（CSP） was prepared.The diphenylmethane diisocyanate（MDI） was applied for the first time in the immobilization of 2,6-dimethyl-b-CD onto the surface of aminized silica gel under mild conditions. The composite materials obtained were used as the CSP for chiral separation processes and this kind of CSP exhibits good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.

关 键 词：2 6-Dimethyl-b-cyclodextrin Chiral stationary phase（CSP） Diphenylmethane diisocyanate（MDI） Chiral separation 

分 类 号：O657.72[理学—分析化学] O636.1[理学—化学]