Synthesis of tetrahydro-β-carbolines from phthalic anhydrides and tryptamine  

作　　者：Yan-Ni Sun Cui-Ling Wang Ning Zhang Zheng Wang Zhu-Lan Liu Jian-Li Liu 

机构地区：[1]Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University

出　　处：《Chinese Chemical Letters》2014年第11期1503-1506,共4页中国化学快报（英文版）

基　　金：the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1174);the National Natural Science Foundation of China(Nos.20872118,30070905);the Key Lab Fund of Shaanxi Province of China(Nos.2010JS097,11JS090,12JS110);the Foundation of the Education Department of Shaanxi Province(No.12JK1010)

摘　　要：Tetrahydro-b-carbolines with strictosamide skeleton have been synthesized via intermolecular condensation, selective reduction, and intramolecular cyclization starting from phthalic anhydrides and tryptamine. The reactions are carried out under mild conditions with a wide range of substrates and functional groups.Tetrahydro-b-carbolines with strictosamide skeleton have been synthesized via intermolecular condensation, selective reduction, and intramolecular cyclization starting from phthalic anhydrides and tryptamine. The reactions are carried out under mild conditions with a wide range of substrates and functional groups.

关 键 词：Phthalic anhydride Tryptamine Tetrahydro-b-carboline Strictosamide 

分 类 号：O626[理学—有机化学]