One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones  

作　　者：Mohammad Piltan 

机构地区：[1]Department of Chemistry, Sanandaj Branch, Islamic Azad University

出　　处：《Chinese Chemical Letters》2014年第11期1507-1510,共4页中国化学快报（英文版）

基　　金：Sanandaj Branch,Islamic Azad UniversityResearch Council for the financial support of this research

摘　　要：A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.

关 键 词：Pyrrolo[1 2-a]quinoxaline a-Bromo ketones 1 2-Diamines Ethyl pyruvate 

分 类 号：O626.13[理学—有机化学]