6min步行运动训练对射血分数保留的心力衰竭患者脑钠肽水平的影响  

The effects of six-minute walking exercise on plasma brain natriuretic peptide(BNP) levels of heart failure patients with preserved ejection fraction

作　　者：任春琦 张盼[2] 

机构地区：[1]北京市顺义区医院心内科,北京101300 [2]北京市平谷区医院心内科,北京101200

出　　处：《中国现代医生》2014年第33期137-139,142,共4页China Modern Doctor

摘　　要：目的探讨6 min步行运动训练对射血分数保留的心力衰竭(HFp EF)患者血浆脑钠肽水平(BNP)的影响。方法随机将50例HFp EF患者分为训练组及对照组,每组25例。两组患者均给予常规药物治疗,训练组辅以6 min步行运动训练。6个月后观察两组治疗前后BNP水平及6 min步行距离(6-MWD)。结果两组患者治疗后BNP水平均有改善(P<0.05);训练组BNP水平显著低于对照组(P<0.05)。结论 6 min步行运动训练能显著改善射血分数保留的心衰患者的BNP水平,有益于提高患者的生活质量。Objective To investigate the effects of 6-minute walking exercise（6-MWE） on plasma brain natriuretic peptide（BNP） levels of heart failure patients with preserved ejection fraction（HFp EF）. Methods Fifty patients with HFp EF were random Ly divided into an exercise training group and control group with 25 cases in each.Each group was treated with routine drugs,and the exercise training group was treated plus 6-MWE.Before and after the six-month,plasma BNP levels and 6-MWD were determined. Results Plasma BNP levels of each group were all improved significantly（P〈0.05）.Plasma BNP level of the exercise training group was lower than the control group＇s（P〈0.05）.Conclusion 6-MWE can significantly decrease the BNP-level of HFp EFs.Walking can increase the quality of life.

关 键 词：射血分数 心力衰竭 6 min步行运动训练 脑钠肽 

分 类 号：R541.6[医药卫生—心血管疾病]