COPD患者血清甲状腺激素变化的临床分析  

Clinical analysis of serum thyroid hormone changes in COPD patients

作　　者：张雷[1] 

机构地区：[1]江苏省宿迁市中医院呼吸科,江苏宿迁223800

出　　处：《中国现代医生》2014年第33期140-142,共3页China Modern Doctor

摘　　要：目的探讨AECOPD治疗前后血清中甲状腺激素水平的改变与AECOPD病情严重程度及预后的关系。方法选择116例COPD患者作为研究对象。入院治疗前空腹测定血清甲状腺激素水平,治疗好转后复查血清甲状腺激素水平。结果 116例患者中死亡2例(1.7%),好转114例(98.3%)。AECOPD患者严重程度不同,血清中T3、FT3比较有显著差异(P<0.05),治疗前后血清中T3、FT3变化较大,有显著差异(P<0.05),而血清中T4、FT4及TSH变化不大,差异无统计学意义(P>0.05)。结论 AECOPD患者体内甲状腺激素分泌水平发生变化与AECOPD病情严重程度呈正相关。因此甲状腺激素水平的检测对COPD病情判断及预后具有重要的临床意义。Objective To investigate the relationship between serum thyroid changes and severity and prognosis in patients with COPD before and after treatment. Methods A total of 116 COPD patients were chosen as research subjects and measuring their serum thyroid hormone levels on empty stomach before and after treatment. Results Two cases of116 patients were dead（1.7%） and 114 cases were improved. T3 and FT3 in serum changes have statistical significance in AECOPD patients with different severity. T3 and FT3 had been largely changed before and after treatment. But there is no changes in T4 、FT4 and TSH and with no statistical significance. Conclusion There is a positive correlation between serum thyroid hormone changes and severity in patients with COPD. Therefore, detection of thyroid hormone levels has important clinical implications for judging severity and prognosis.

关 键 词：COPD急性期 甲状腺激素 临床意义 

分 类 号：R563.3[医药卫生—呼吸系统]