嘉兴市儿童肺炎支原体IgM抗体结果分析  

Mycoplasma pneumoniae-IgM antibody children in Jiaxing City

作　　者：孙丽[1] 李红胜[1] 陆红霞[1] 

机构地区：[1]浙江省嘉兴市第二医院检验科,浙江嘉兴314000

出　　处：《中国妇幼健康研究》2014年第5期788-790,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的分析嘉兴市儿童肺炎支原体(MP)感染规律,为临床早期诊断、早期治疗提供依据。方法采用酶联免疫吸附测定法(ELISA)法,对2011年12月至2012年11月间在嘉兴市第二医院就诊的0~12岁吸道感染惠儿2 275例进行肺炎支原体免疫球蛋白M抗体(MP-IgM抗体)检测,并分析<1岁、1~6岁和~12岁年龄组及全年4个季度患儿MP-IgM抗体的阳性检出率。结果 2 275例呼吸道感染患儿,检出MP-IgM抗体阳性295例,阳性率为12.97%,其中<1岁、1~6岁和~12岁年龄组患儿MP-IgM抗体阳性检出率分别为8.88%(30/338)、13.67%(205/1 500)和13.73%(60/437);1岁以内患儿MP-IgM抗体阳性率均低于其它两个年龄组,差异具有统计学意义(x^2值分别为5.673和4.371,均P<0.05),1~6岁和~12岁两组比较差异无统计学意义(x^2=0.001,P>0.05)。4个季度阳性检出率分别为14.44%(65/450)、12.36%(83/671)、9.82%(40/407)和14.20%(107/747),差异均有统计学意义(x^2=10.462,P<0.05)。结论 MP感染的患儿以学龄前儿童及学龄期儿童为主,一年四季均可发病,第3季度最低,第一、第4季度较高。Objective To analyze the ligatures of mycoplasma pneumoniae （MP） in children in Jiaxing so as to provide basis for early diagnosis and treatment. Methods Enzyme-linked immunosorbent assay （ELISA） method was used to detect MP IgM antibody in 2 275 infected cases aged 0 - 12 years old admitted in the Second Hospital of Jiaxing during December 2011 and November 2012. The positive detection rate of three groups （group aged 〈 lyear, group aged 1 -6 years, group aged 7 - 12 years） and in four quarters were analyzed. Results Among 2 275 infected children, 295 cases were found with positive MP-IgM antibody, and the positive rate was 12.97%. The detection rate of positive MP-IgM antibody in three groups was 8.88% （30/338）, 13.67% （205/1 500） and 13.73% （60/437）, respectively. The positive rate of MP-IgM antibody of the group aged 〈 1 year was lower than the other two groups, and the difference was significant （X2 value was 5. 673 and 4. 371, respectively, both P 〈 0.05 ）. But there was no significant difference between the group aged 1-6 years and the group aged 7-12 years （X^2 = 0. 001, P 〉 0.05 ）. The positive rate of four quarters was 14.44% （65/450） , 12.36% （83/671）, 9.82% （40/407） and 14.20% （107/747）, respectively, and the ditterence among them was significant （X^2 = 10. 462,P 〈 0.05）. Conclusion Most Mp infections occur in school-aged children and preschool children. It may onset throughout the year. At the third quarter the incidence is lowest, but it is relatively high at the first and fourth quarter.

关 键 词：肺炎支原体 IGM抗体 酶联免疫吸附测定法 儿童 

分 类 号：R446.62[医药卫生—诊断学] R725.6[医药卫生—临床医学]