硬膜外不同输注方式对带状疱疹后神经痛的治疗效果  

EFFECTS OF DIFFERENT EPIDURAL BLOCKS ON THE POSTHERPETIC NEURALGIA PATIENTS

作　　者：王钧[1] 樊碧发[2] 冯志斌[3] 

机构地区：[1]冀中能源峰峰集团总医院介入科,邯郸056201 [2]北京中日友好医院疼痛科,北京100029 [3]冀中能源峰峰集团总医院骨科,邯郸056200

出　　处：《中国疼痛医学杂志》2014年第10期725-728,共4页Chinese Journal of Pain Medicine

摘　　要：目的:比较持续性和间断性硬膜外镇痛两种方法对带状疱疹后神经痛(postherpetic neuralgia,PHN)的治疗效果,并评估其临床应用价值。方法:选择符合标准的PHN患者96例,随机分为A、B两组,A组患者予以持续硬膜外镇痛,B组患者予以间断硬膜外镇痛。分别于治疗前和治疗后2、4、8、14天,共5次对A组和B组的患者采用视觉模拟评分(Visual analogue scale,VAS)进行评价,并观察两种治疗方法的并发症,以及需要执行补救措施的病例数。结果:两组治疗后2、4、8、14天的VAS评分,组间对照无显著性差异。两组治疗前和治疗后各时间点的VAS评分,组内对照存在显著性差异。B组患者除1例患者发生导管脱出外未出现其它明显的不良反应。结论:两种治疗方法对PHN均有一定的效果,且治疗效果无明显的差异,可以酌情采取合适的方式。Objective： To compare the effect of continuous and intermittent epidural block in the treatment of postherpetic neuralgia （PHN）, and to evaluate the clinical outcomes. Methods： A total of 96 patients with PHN were randomly divided into two groups： group A and group B. Patients were treated with continuous （group A） and intermittent （group B） epidural block. Patients were asked to rate their pain with Visual analogue scale （VAS） before and 2, 4, 8 and 14 days after treatment. Complications of the two groups were also observed. Results： There was no significant difference in VAS between the two groups on 2, 4, 8 and 14 days treatment （P 〉 0.05） but there was significant difference in VAS before and after the treatment in both groups. No obvious complications were observed in either of the two groups except 1 case of catheter extrusion in group B. Conclusion： Continuous and intermittent epidural block have equal therapeutic effects on PHN.

关 键 词：硬膜外阻滞 持续性 间断性 带状疱疹后神经痛 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]