2％夫西地酸乳膏多中心治疗细菌性皮肤病安全性分析  

Safety analysis of 2％ fusidic acid cream in multi-center treatment of bacterial skin disease

作　　者：于云和 

机构地区：[1]河南省新野县人民医院皮肤科,473500

出　　处：《中国实用医刊》2014年第23期35-36,共2页Chinese Journal of Practical Medicine

摘　　要：目的 探讨采用2％夫西地酸乳膏治疗细菌性皮肤病的临床疗效和安全性.方法 随机选取2010年5月至2013年7月新野县人民医院收治的确诊为细菌性皮肤病患者146例,随机平均分为实验组和对照组,按照多中心开放性实验原则,实验组采用2％夫西地酸乳膏治疗,对照组采用2％莫匹罗星软膏治疗,对治疗结果进行分析.结果 本研究实验组治疗总有效率（95.9％）明显高于对照组（78.1％）,差异有统计学意义（P＜0.05）;实验组治疗期间未发生不良症状,对照组4例出现局部灼热和瘙瘁感,一段时间后症状自行消失.结论 采用2％夫西地酸乳膏对细菌性皮肤病患者进行治疗,疗效显著,安全可靠,建议在临床上进一步推广.Objective To investigate the clinical efficacy and safety of 2％ fusidic acid cream in the treatment of bacterial skin disease.Methods Randomly selected 146 patients who were diagnosed as bacterial skin diseases in Xinye county people＇ s hospital from May 2010 to July 2013,they were randomly divided into experimental group and control group.In accordance with the principles of multi-center open experiment,the experimental group was taken 2 ％ fusidic acid cream,the control group was taken 2％ mupirocin ointment.And the treatment results of the two groups were analyzed.Results The total efficiency of the experimental group （95.9％） was significantly higher than that of control group （78.1％）,the difference was significant（P ＜0.05）.Adverse symptoms did not occur during the treatment in the experimental group,there were four patients had local burning and itching during treatment in control group,and the symptoms disappeared later.Conclusions Using 2％ fusidic acid cream in treating bacterial skin diseases has significant effect,it is safe and reliable,and it is recommended to be further promote in clinical practice.

关 键 词：细菌性皮肤病 2%夫西地酸乳膏 安全性 

分 类 号：R753[医药卫生—皮肤病学与性病学]