石墨烯/铂纳米粒子杂化膜测定肾上腺素  

Determination of Epinephrine by Graphene / Platinum Nanoparticle Hybrid Membrane Modified Electrode

作　　者：郭宪厚[1,2] 王学亮[1] 郁章玉[1,3] 

机构地区：[1]菏泽学院化学化工系,菏泽274000 [2]枣庄矿业集团宏达化工有限公司,滕州277500 [3]济宁学院,曲阜273165

出　　处：《应用化学》2014年第12期1465-1471,共7页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(21105023);山东省自然科学基金(BS2013HZ027;ZR2009BM003)资助项目~~

摘　　要：利用循环伏安法制备了石墨烯/铂纳米粒子杂化膜修饰电极,并利用该修饰电极研究了肾上腺素（EP）的电化学行为,建立了测定肾上腺素的电化学方法。分别利用扫描电子显微镜和循环伏安法对电极的表面形貌和电化学性能进行了表征,优化了修饰电极制备过程中影响电极性能的条件和EP的测定条件。结果表明,石墨烯/铂纳米粒子修饰电极对肾上腺素有明显的电催化作用。在p H=5.0的柠檬酸-磷酸氢二钠缓冲溶液中,EP的氧化峰电流与其浓度在4.4×10^-8~2.2×10^-6mol/L的范围内呈良好的线性关系。线性方程为ipa（10 A）=0.0753c（mol/L）＋3.7653×10^-5,r=0.9989,检出限为2.2×10^-9mol/L（S/N=3）。修饰电极表具有良好的重现性,可用于实际样品的测定。Graphene/platinum nanoparticles hybrid membrane modified electrode was prepared by cyclic vohammetry（ CV ）. The electrochemical behaviors of epinephrine （EP） were studied on this modified electrode, and an electrochemical method for determination of EP was developed. The morphology and the electrochemical properties of the modified electrode were characterized by scan electron microscopy （SEM） and cyclic vohammetry, respectively. The conditions that influence the electrochemical properties of the modified electrode during the preparation processes and the conditions for determination of EP were optimized. Experimental results show that the modified electrode has excellent catalytic properties for the redox of EP. In the Na2HPO4-citric acid buffer solution （ pH = 5.0 ）, the oxidative peak current of EP is linear with its concentration in the range of 4.4 ×10^-8 ~2. 2 ×10^-6 mol/L. The linear regressive equation is ipa （10 A） = 0. 0753c（mol/L） ＋ 3.7653 ×10^-5 with r =0. 9989, and the detection limit of 2.0 ×10^-9 moL/L（ S/N = 3 ）. The modified electrode shows good reproducibility, high sensitivity and selectivity. It could be used for determination of the content of EP in real samples.

关 键 词：石墨烯 铂纳米粒子 杂化材料 肾上腺素 应用 

分 类 号：O657.1[理学—分析化学]