傅里叶变换红外光谱对药品中沙门菌的鉴别  

Classification and Cluster Analysis of Salmonella spp. by FT-IR

作　　者：周爽[1] 钱文静[1] 

机构地区：[1]江苏省食品药品检验所,南京210008

出　　处：《中国药品标准》2014年第5期348-352,共5页Drug Standards of China

摘　　要：目的：应用傅里叶变换红外光谱技术对30个含动物组织的中成药中的沙门菌进行鉴别。方法：用傅里叶红外变换光谱对30个中成药中的沙门菌进行指纹图谱数据采集，用聚类分析方法进行比较。结果：确定了1200～900，3000～2800，1500～1400 cm^-1三个特征谱区，并在此基础上进行聚类分析，使菌株得到较准确的归类。结论：傅里叶红外变换光谱具有快速、准确、方便等优点，且重现性高，是药品中控制沙门菌的一个重要补充方法。Objective：To classify 30 strains of Salmonella spp.from different Chinese patent medicines by fourier transform infrared spectroscopy （ FT-IR）.Methods：FT-IR fingerprint absorption spectra of 30 strains of Salmonella spp.were collected and analyzed by cluster methods.Results：Significant spectra differences amongs these strains were observed among the wavenumber regions of 1200-900,3000-2800 and 1500-1400 cm^-1.According to the representative bands of these regions, cluster analysis were executed to classify the FT-IR spectra.Conclusion：As a rapid, accurate, easy-to-use and reproducible technique, FT-IR is an important supplement to the conctrol of Salmonella spp.for drug detection.

关 键 词：傅里叶红外光谱 沙门菌 聚类分析 鉴别 

分 类 号：R921.2[医药卫生—药学]