致尿路感染大肠埃希菌的耐药监测及分析  

Detection and Analysis of Drug Resistance of Escherichia Coli Causing Urinary Tract Infection

作　　者：江杨华[1] 欧阳晓玲 熊劲芝[1] 张林[1] 黄红卫[1] 李艳[1] 

机构地区：[1]湖南省郴州市第一人民医院,423000

出　　处：《医学理论与实践》2014年第19期2531-2533,共3页The Journal of Medical Theory and Practice

摘　　要：目的:了解尿路感染患者尿液标本中大肠埃希菌的检出情况和耐药情况,指导临床合理用药。方法:采用回顾性分析,对2013年1年来医院尿路感染患者进行调查研究。结果:尿液培养分离的814株病原菌中,大肠埃希菌260株,占总数的31.9%,其中,产ESBLs大肠埃希菌124株,占47.7%。药敏结果显示,产ESBLs大肠埃希菌耐药率明显高于非产ESBLs大肠埃希菌。结论:产ESBLs大肠埃希菌的增多,加重了细菌的耐药性,临床在治疗尿路感染时应综合考虑大肠埃希菌产ESBLs的危险因素及药敏结果合理使用抗生素。Objective：Investigating the pathogens and its drug resistances of Escherichia coli causing urinary tract infection in order to provide a practical method for the disease control and clinical drug use.Methods：Patients with urinary tract infection in 2014 were investigated using retrospective method.Results：In the 814 pathogen strains isolated from urine,260 strains were Escherichia coli,accounting for 31.9%of the total,among which 124 strains carrying ESBLs accounted for 47.7%.The results of the drug sensitive test showed that the resistances of the Escherichia coli carrying ESBLs were much higher than which not.Conclusion：With the increase of the amounts of Escherichia coli carrying ESBLs,the resistances of the pathogen were more serious,which made the doctors should take the dangerous factors causing Escherichia coli producing ESBLs and the results of the drug sensitive test into consideration when treating the patients of Urinary tract infection.

关 键 词：尿路感染 大肠埃希菌 耐药性 超广谱B-内酰胺酶 

分 类 号：R691.3[医药卫生—泌尿科学]