钽棒植入联合自体骨髓间充质干细胞移植治疗早期股骨头缺血性坏死  

Early Clinical Results of Implantation of Tantalum Rod Combined Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells for Early Stage of Avascular Necrosis of Femoral Head

作　　者：梁红锁[1] 黄克[1] 李林[1] 张波[1] 韦程寿[1] 

机构地区：[1]广西医科大学第三附属医院骨一科,广西南宁市530031

出　　处：《医学理论与实践》2014年第19期2534-2535,2540,共3页The Journal of Medical Theory and Practice

摘　　要：目的：观察钽棒植入联合自体骨髓间充质干细胞移植治疗早期股骨头缺血性坏死的临床疗效。方法：对27例ARCOⅠ、Ⅱ期的ANFH患者采用股骨头髓芯减压后植入钽棒并联合自体骨髓间充质干细胞移植。结果：所有患者经过7～24个月（平均13个月）的随访,关节疼痛基本消失,活动范围接近或恢复正常,除2例患者进展为ARCOⅢ期外,其余股骨头均无塌陷,影像学检查结果示股骨头囊性变消失,Harris评分由术前的（54.2±7.1）分提高到术后（83.9±8.6）分。结论：钽棒植入联合自体骨髓间充质干细胞移植治疗早期股骨头缺血性坏死,具有创伤小、疗效确切等优点,近期临床疗效良好。Objective：To study the effects of implantation of tantalum rod and transplantation of autologous bone marrow mesenchymal stem cells for early stage of avascular necrosis of femoral head.Methods：27patients with avascular necrosis of femoral head in the early stage were treated with implantation of tantalum rod and transplantation of autologous bone marrow mesenchymal stem cells.Results：The average period of follow-up was thirteen months（7～24months）.Pain of all patients disappeared.The movement range of the hip joint was normal or approximate to normal.Except two cases evolved to stage of ARCOⅢ,X-ray showed that cystic degeneration disappeared.The Harris score was 54.2±7.1before operation and it increased significantly to 83.9±8.6after operation.Conclusion：It has the advantage to minimal damage of implantation of tantalum rod and transplantation of autologous bone marrow mesenchymal stem cells for early stage of avascular necrosis of femoral head.It is an effective way for the treatment of femoral head necrosis.The short-term efficacy is good.

关 键 词：股骨头坏死 骨髓间充质干细胞 钽棒 

分 类 号：R681.8[医药卫生—骨科学]