美丽芍药化学成分  

Chemical Compositions of Paeonia mairei

作　　者：石钰[1] 马养民[1] 康永祥[2] 王宁辉[1] 

机构地区：[1]陕西科技大学化学与化工学院,教育部轻化工助剂化学与技术重点实验室,西安710021 [2]西北农林科技大学林学院,陕西杨凌712100

出　　处：《中国实验方剂学杂志》2014年第23期104-106,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家公益性行业(林业)科研专项(200904004)

摘　　要：目的:研究太白山地区美丽芍药Paeonia mairei的化学成分,为其药理研究与作用机制提供依据。方法:采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、重结晶等方法分离纯化化合物,并通过化合物的理化性质和波谱分析鉴定其结构。结果:从美丽芍药中分离得到8个化合物,分别为β-谷甾醇(1),齐墩果酸(2),常春藤皂苷元(3),胡萝卜苷(4),大黄酚(5),苯甲酸(6),没食子酸(7),没食子酸乙酯(8)。结论:化合物5为从该属植物中首次分离得到,其余化合物均为首次从该植物中得到。Objective ： To stu supply material basis for its pharmaco dy gic the chemical constituents of Paeonia mairei in Taibai mountains and to al research and therapeutic mechanism. Method： The compounds from P. mairei were isolated and purified by silica gel column chromatography, Sephadex LH-20 column chromatography and recrystallization method, and their structures were elucidated on the basis of their physicochemical properties and spectra analysis. Result： Eight compounds were obtained and identified as β-sitosterol （1） , oleanic acid （2）, hederagenin （3）, daueosterol （4）, chrysophanol （5）, benzoic acid （6）, gallic acid （7）, ethyl gallate （8）. Conclusion： Compound 5 were obtained from the genus for the first time. The rest of the compounds was isolated from the plant of P. mairei for the first time.

关 键 词：芍药属 美丽芍药 化学成分 结构鉴定 

分 类 号：R284.1[医药卫生—中药学]